Kanno Atsushi, Masamune Atsushi, Hanada Keiji, Kikuyama Masataka, Kitano Masayuki
Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC), Onomichi 722-8508, Japan.
Diagnostics (Basel). 2019 Feb 5;9(1):18. doi: 10.3390/diagnostics9010018.
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. PDAC is the fourth leading cause of death in the United States and Japan based on epidemiological data. Early detection of PDAC is very important to improve the prognosis of PDAC. Early detection of pancreatic ductal adenocarcinoma (PDAC) requires further examination after selecting cases with risk factors for the condition, such as family history, hereditary pancreatic carcinoma syndrome, intraductal papillary mucinous neoplasms, or chronic pancreatitis. The Japan Study Group on the Early Detection of Pancreatic Cancer has investigated and clarified the clinicopathological features for the early diagnosis of PDAC. In Japan, an algorithm for the early diagnosis of PDAC, which utilized the cooperation of local clinics and regional general hospitals, has been a breakthrough in the detection of early-stage PDAC. Further approaches for the early diagnosis of PDAC are warranted.
胰腺导管腺癌（PDAC）是一种致命疾病。根据流行病学数据，PDAC是美国和日本第四大死因。早期发现PDAC对于改善其预后非常重要。早期发现胰腺导管腺癌（PDAC）需要在选择具有该疾病危险因素的病例后进行进一步检查，这些危险因素包括家族史、遗传性胰腺癌综合征、导管内乳头状黏液性肿瘤或慢性胰腺炎。日本胰腺癌早期检测研究小组已经对PDAC早期诊断的临床病理特征进行了调查并予以明确。在日本，一种利用当地诊所和地区综合医院合作的PDAC早期诊断算法，在早期PDAC检测方面取得了突破。有必要采取进一步的方法来早期诊断PDAC。
