Nordlind K, Mutt V, Sundström E
Department of Dermatology, Karolinska Hospital, Stockholm, Sweden.
Brain Behav Immun. 1988 Dec;2(4):282-92. doi: 10.1016/0889-1591(88)90030-x.
Neuropeptides and monoamines have been found in tissues where immune reactions are initiated such as the skin, gut, and respiratory tract, and in these tissues neuropeptides and monoamines might be involved in the regulation of lymphocyte activation. Studies both in in vitro and in vivo showing that various neuropeptides and monoamines may influence reactions such as T lymphocyte proliferation, B lymphocyte proliferation, and antibody synthesis, lymphocyte migration, and cytotoxicity will be reviewed.
人们已在引发免疫反应的组织(如皮肤、肠道和呼吸道)中发现了神经肽和单胺,在这些组织中,神经肽和单胺可能参与淋巴细胞活化的调节。本文将综述体外和体内研究,这些研究表明各种神经肽和单胺可能影响T淋巴细胞增殖、B淋巴细胞增殖、抗体合成、淋巴细胞迁移和细胞毒性等反应。