Department of Sciences, University of Basilicata, Potenza, Italy.
Mol Reprod Dev. 2019 Oct;86(10):1307-1323. doi: 10.1002/mrd.23123. Epub 2019 Feb 14.
Global warming represents a major stressful environmental condition that compromises the reproductive efficiency of animals and humans via a rise of body temperature above its physiological homeothermic point (heat stress [HS]). The injuries caused by HS on reproductive function involves both male and female components, fertilization mechanisms as well as the early and late stages of embryo-fetal development. This occurrence causes great economic damage in livestock, and, in wild animals creates selective pressure towards the advantages of better-adapted genotypes to the detriment of others. Humans undergo several types of stress, including heat, and these represent putative causes of ongoing progressive decay in procreation; an increasing number of remedies in the form of antioxidant preparations are now being proposed to counteract the effects of stress. This review aims to describe the results of the most recent studies that aimed to highlight these effects and to draw information on the mechanisms acting as the basis of this problem from a comparative analysis.
全球变暖代表了一种主要的应激环境条件，它会通过体温升高超过生理恒温点（热应激[HS]）来降低动物和人类的生殖效率。HS 对生殖功能造成的损伤涉及男性和女性成分、受精机制以及胚胎-胎儿发育的早期和晚期阶段。这种情况在畜牧业中造成了巨大的经济损失，而在野生动物中，它对更好适应基因型的优势产生了选择性压力，而牺牲了其他基因型。人类会经历多种类型的应激，包括热应激，这些应激被认为是生殖功能持续衰退的潜在原因；现在有越来越多的抗氧化剂制剂形式的补救措施被提出，以抵消应激的影响。本综述旨在描述最近旨在强调这些影响的研究结果，并从比较分析中获取有关作为该问题基础的机制的信息。
