School of Metallurgy and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou, 341000, China.
Mikrochim Acta. 2019 Feb 15;186(3):189. doi: 10.1007/s00604-019-3299-7.
A nanocomposite is described that consists of TmPO and graphene oxide (GO) and is used to modify a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). GO and TmPO were synthesized via the Hummers method and by a hydrothermal method, respectively. The nanocomposite was characterized by transmission electron microscopy, energy dispersive X-ray spectroscopy, powder X-ray diffraction and Fourier transform infrared spectroscopy. The electrochemical properties of the modified GCE were studied by electrochemical impedance spectroscopy and cyclic voltammetry. The good performance of the modified GCE results from the synergistic effects between GO with its good electrical conductivity and of TmPO as the electron mediator that accelerates the electron transfer rate. Compared to a bare GCE, a GO/GCE and a TmPO/GCE, the GO/TmPO/GCE exhibits three well-defined and separated oxidation peaks (at -0.05, +0.13 and + 0.26 V vs. SCE). Responses to AA, DA and UA are linear in the 0.1-1.0 mM, 2-20 μM and 10-100 μM concentration ranges, respectively. Graphical abstract Schematic presentation of a nanocomposite that consists TmPO and graphene oxide (GO) and is used to modify a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA).
一种由 TmPO 和氧化石墨烯（GO）组成的纳米复合材料被用于修饰玻碳电极（GCE），以获得一种同时测定抗坏血酸（AA）、多巴胺（DA）和尿酸（UA）的传感器。GO 和 TmPO 分别通过 Hummers 法和水热法合成。通过透射电子显微镜、能量色散 X 射线光谱、粉末 X 射线衍射和傅里叶变换红外光谱对纳米复合材料进行了表征。通过电化学阻抗谱和循环伏安法研究了修饰后的 GCE 的电化学性质。修饰后的 GCE 性能良好，这是由于 GO 具有良好的导电性和 TmPO 作为电子媒介物的协同作用，加速了电子转移速率。与裸 GCE、GO/GCE 和 TmPO/GCE 相比，GO/TmPO/GCE 显示出三个清晰且分离的氧化峰（在-0.05、+0.13 和+0.26 V 相对于 SCE）。AA、DA 和 UA 的响应在 0.1-1.0 mM、2-20 μM 和 10-100 μM 浓度范围内呈线性关系。
