Chen Xuan, Li Na, Rong Yanqin, Hou Yuli, Huang Yu, Liang Wenting
Department of Neurology, Taiyuan Central Hospital of Shanxi Medical University Taiyuan 030062 China.
Institute of Environmental Science, Shanxi University Taiyuan 030006 China
RSC Adv. 2021 Aug 19;11(45):28052-28060. doi: 10.1039/d1ra02313f. eCollection 2021 Aug 16.
A three-dimensional reduced graphene oxide nanomaterial with β-cyclodextrin modified glassy carbon electrode (3D-rGO/β-CD/GCE) was constructed and used to detect the electrochemical behavior of dopamine (DA). The nanocomposite materials were characterized by scanning electron microscopy (SEM), infrared spectrometry (FT-IR), Raman spectrogram and thermogravimetric analysis (TGA), which showed that β-CD was well modified on 3D graphene with a porous structure. The electrochemical properties of different modified electrodes were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), proving the highest electron transfer rate of the 3D-rGO/β-CD modified electrode. The experimental conditions such as scan rate, pH, enrichment time and layer thickness were optimized. Under the best experimental conditions, DA was detected by differential pulse voltammetry (DPV) by 3D-rGO/β-CD/GCE with excellent electrocatalytic ability and satisfactory recognition ability, resulting in a wide linear range of 0.5-100 μM and a low detection limit (LOD) of 0.013 μM. The modified electrode based on 3D-rGO/β-CD nanocomposites is promising in the field of electrochemical sensors due to its high sensitivity and other excellent properties.
构建了一种具有β-环糊精修饰玻碳电极的三维还原氧化石墨烯纳米材料（3D-rGO/β-CD/GCE），并用于检测多巴胺（DA）的电化学行为。通过扫描电子显微镜（SEM）、红外光谱（FT-IR）、拉曼光谱和热重分析（TGA）对纳米复合材料进行了表征，结果表明β-环糊精很好地修饰在了具有多孔结构的三维石墨烯上。通过循环伏安法（CV）和电化学阻抗谱（EIS）研究了不同修饰电极的电化学性质，证明了3D-rGO/β-CD修饰电极具有最高的电子转移速率。对扫描速率、pH值、富集时间和层数等实验条件进行了优化。在最佳实验条件下，采用3D-rGO/β-CD/GCE通过差分脉冲伏安法（DPV）检测DA，具有优异的电催化能力和令人满意的识别能力，线性范围宽达0.5-100μM，检测限低至0.013μM。基于3D-rGO/β-CD纳米复合材料的修饰电极因其高灵敏度和其他优异性能在电化学传感器领域具有广阔前景。
