文明病——癌症、糖尿病、肥胖症和痤疮——牛奶、胰岛素样生长因子-1（IGF-1）和哺乳动物雷帕霉素靶蛋白复合体1（mTORC1）的影响
Diseases of Civilization - Cancer, Diabetes, Obesity and Acne - the Implication of Milk, IGF-1 and mTORC1.
作者信息
Clatici Victor Gabriel, Voicu Cristiana, Voaides Catalina, Roseanu Anca, Icriverzi Madalina, Jurcoane Stefana
机构信息
Dermalife Medical Centre, Bucharest, Romania.
UASVM Bucharest, Faculty of Biotechnologies, Bucharest, Romania.
出版信息
Maedica (Bucur). 2018 Dec;13(4):273-281. doi: 10.26574/maedica.2018.13.4.273.
Abstract
Nutrition and food are one of the most complex aspects of human lives, being influenced by biochemical, psychological, social and cultural factors. The Western diet is the prototype of modern dietary pattern and is mainly characterized by the intake of large amounts of red meat, dairy products, refined grains and sugar. Large amounts of scientific evidence positively correlate Western diet to acne, obesity, diabetes, heart disease and cancer, the so-called "diseases of civilization". The pathophysiological common ground of all these pathologies is the IGF-1 and mTORC pathways, which will be disscussed further in this paper.
摘要
营养与食物是人类生活中最复杂的方面之一，受到生物化学、心理、社会和文化因素的影响。西方饮食是现代饮食模式的原型，其主要特点是大量摄入红肉、乳制品、精制谷物和糖。大量科学证据表明西方饮食与痤疮、肥胖、糖尿病、心脏病和癌症等所谓的“文明病”呈正相关。所有这些病症的病理生理共同基础是IGF-1和mTORC途径，本文将进一步讨论。
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