膳食纤维与肠易激综合征风险：一项病例对照研究。
Dietary fiber and risk of irritable bowel syndrome: a case-control study.
作者信息
Hosseini Oskouie Fatemeh, Vahedi Homayoun, Shahrbaf Mohammad Amin, Sadeghi Amir, Rashidkhani Bahram, Hekmatdoost Azita
机构信息
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Digestive Disease Research Center, Digestive Disease Research Institute, Tehran, Iran.
出版信息
Gastroenterol Hepatol Bed Bench. 2018 Winter;11(Suppl 1):S20-S24.
AIM
The purpose of this study was to determine the relationship between dietary fiber intake and risk of irritable bowel syndrome (IBS).
BACKGROUND
Patients with IBS are usually concerned about their diet, which can exacerbate or relieve their symptoms.
METHODS
In this case-control study, ninety cases and 355 controls were selected from a gastroenterology clinic. Dietary intakes of participants were assessed using a validated and reliable food frequency questionnaire (FFQ). Dietary fiber was calculated according to United States Department of Agriculture (USDA) food composition table.
RESULTS
Dietary total fiber intake was significantly associated with lower risk of IBS. The adjusted odds ratio (OR) comparing the highest tertile of dietary total fiber with the lowest tertile was 0.14 (95% CI = 0.71-0.28; P-test for trend <0.001); however, there was no significant association or dose-response trend for higher intakes of soluble, and insoluble fiber separately with risk of IBS.
CONCLUSION
Our data indicate that dietary fiber is inversely associated with the risk of IBS. Further prospective studies are needed to confirm these data.
目的
本研究旨在确定膳食纤维摄入量与肠易激综合征（IBS）风险之间的关系。
背景
IBS患者通常关注自己的饮食，饮食可加重或缓解其症状。
方法
在这项病例对照研究中，从胃肠病诊所选取了90例病例和355例对照。使用经过验证且可靠的食物频率问卷（FFQ）评估参与者的饮食摄入量。膳食纤维根据美国农业部（USDA）食物成分表计算。
结果
膳食纤维总摄入量与IBS风险较低显著相关。将膳食纤维总摄入量最高三分位数与最低三分位数进行比较的调整优势比（OR）为0.14（95%置信区间=0.71-0.28；趋势P检验<0.001）；然而，单独较高的可溶性和不溶性纤维摄入量与IBS风险之间没有显著关联或剂量反应趋势。
结论
我们的数据表明膳食纤维与IBS风险呈负相关。需要进一步的前瞻性研究来证实这些数据。
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