Oppenheim Ben, Gallivan Mark, Madhav Nita K, Brown Naor, Serhiyenko Volodymyr, Wolfe Nathan D, Ayscue Patrick
Metabiota, San Francisco, California, USA.
BMJ Glob Health. 2019 Jan 29;4(1):e001157. doi: 10.1136/bmjgh-2018-001157. eCollection 2019.
Robust metrics for national-level preparedness are critical for assessing global resilience to epidemic and pandemic outbreaks. However, existing preparedness assessments focus primarily on public health systems or specific legislative frameworks, and do not measure other essential capacities that enable and support public health preparedness and response.
We developed an Epidemic Preparedness Index (EPI) to assess national-level preparedness. The EPI is global, covering 188 countries. It consists of five subindices measuring each country's economic resources, public health communications, infrastructure, public health systems and institutional capacity. To evaluate the construct validity of the EPI, we tested its correlation with proxy measures for preparedness and response capacity, including the timeliness of outbreak detection and reporting, as well as vaccination rates during the 2009 H1N1 influenza pandemic.
The most prepared countries were concentrated in Europe and North America, while the least prepared countries clustered in Central and West Africa and Southeast Asia. Better prepared countries were found to report infectious disease outbreaks more quickly and to have vaccinated a larger proportion of their population during the 2009 pandemic.
The EPI measures a country's capacity to detect and respond to infectious disease events. Existing tools, such as the Joint External Evaluation (JEE), have been designed to measure preparedness within a country over time. The EPI complements the JEE by providing a holistic view of preparedness and is constructed to support comparative risk assessment between countries. The index can be updated rapidly to generate global estimates of pandemic preparedness that can inform strategy and resource allocation.
用于衡量国家层面防范能力的稳健指标对于评估全球应对流行病和大流行病爆发的复原力至关重要。然而,现有的防范评估主要侧重于公共卫生系统或特定的立法框架,并未衡量其他有助于并支持公共卫生防范和应对的关键能力。
我们开发了一种流行病防范指数(EPI)来评估国家层面的防范能力。该EPI具有全球性,涵盖188个国家。它由五个子指数组成,分别衡量每个国家的经济资源、公共卫生通信、基础设施、公共卫生系统和机构能力。为了评估EPI的结构效度,我们测试了它与防范和应对能力的替代指标之间的相关性,包括疫情检测和报告的及时性,以及2009年甲型H1N1流感大流行期间的疫苗接种率。
防范能力最强的国家集中在欧洲和北美,而防范能力最弱的国家集中在中非、西非和东南亚。研究发现,防范能力较强的国家在2009年大流行期间报告传染病疫情的速度更快,且其人口接种疫苗的比例更高。
EPI衡量一个国家检测和应对传染病事件的能力。现有的工具,如联合外部评估(JEE),旨在衡量一个国家随时间推移的防范能力。EPI通过提供对防范能力的全面看法对JEE起到补充作用,并且其构建目的是支持国家间的比较风险评估。该指数可以迅速更新,以生成全球大流行防范能力的评估结果,为战略制定和资源分配提供参考。