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双相情感障碍患者的饮食质量和饮食模式。

Diet quality and eating patterns in euthymic bipolar patients.

机构信息

Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznań, Poland.

出版信息

Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1221-1238. doi: 10.26355/eurrev_201902_17016.

Abstract

OBJECTIVE

As mood disorders and obesity are interrelated, and both are linked to increased morbidity and mortality, risk factors for obesity should be identified and closely monitored in patients with bipolar disorder (BD). The aim of this study was to determine the diet quality of BD patients and to investigate its putative associations with comorbid obesity and disorders of carbohydrate metabolism, as well as the relationship between diet and clinical features of BD.

PATIENTS AND METHODS

Eating patterns in 113 euthymic BD patients and 160 healthy control subjects were assessed using data obtained from a food frequency questionnaire. Associations of diet quality with subjects' weight, waist circumference (WC), insulin resistance index and clinical features of BD were also analyzed.

RESULTS

BD patients had lower Mediterranean Diet Score than controls. Using principal analysis, four dietary patterns were revealed in the BD group (western-type, pro-healthy carbohydrates, unhealthy snacks, and meats and potatoes). Over 70% of patients with BD had Body Mass Index above 25kg/m2. The values of Fasting Triglycerides Glucose Index and WC were significantly higher in BD patients than in the control group. No significant association between diet quality indices and the clinical course of BD was found.

CONCLUSIONS

In our work, euthymic bipolar patients showed unhealthy dietary patterns and had lower adherence to the Mediterranean diet than the controls. Increased values of insulin resistance indicators in the BD group point to the necessity of monitoring glucose and triglycerides levels and measurement of waist circumference in bipolar patients in the routine clinical practice. The cooperation between psychiatrists, dieticians and other medical professionals are necessary to develop dietary recommendations for patients with bipolar disorder.

摘要

目的

由于心境障碍和肥胖相互关联,且两者均与发病率和死亡率增加有关,因此应确定双相情感障碍(BD)患者的肥胖风险因素,并对其进行密切监测。本研究旨在确定 BD 患者的饮食质量,并探讨其与肥胖和碳水化合物代谢障碍的关系,以及饮食与 BD 临床特征的关系。

方法

通过食物频率问卷,评估 113 例病情稳定的 BD 患者和 160 例健康对照者的饮食模式。分析饮食质量与患者体重、腰围(WC)、胰岛素抵抗指数和 BD 临床特征的关系。

结果

BD 患者的地中海饮食评分低于对照组。通过主成分分析,在 BD 组中发现了四种饮食模式(西式、促进健康的碳水化合物、不健康的零食和肉和土豆)。超过 70%的 BD 患者 BMI 超过 25kg/m2。BD 患者的空腹甘油三酯葡萄糖指数和 WC 值明显高于对照组。饮食质量指数与 BD 临床病程之间无显著相关性。

结论

在我们的研究中,病情稳定的双相情感障碍患者表现出不健康的饮食模式,对地中海饮食的依从性低于对照组。BD 组胰岛素抵抗指标值升高,表明在常规临床实践中,有必要监测双相情感障碍患者的血糖和甘油三酯水平,并测量腰围。精神科医生、营养师和其他医疗专业人员之间的合作对于为双相情感障碍患者制定饮食建议是必要的。

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