Larussa Tiziana, Rossi Marianna, Suraci Evelina, Marasco Raffaella, Imeneo Maria, Abenavoli Ludovico, Luzza Francesco
Department of Health Sciences, University of Catanzaro "Magna Graecia", Viale Europa, 88100 Catanzaro, Italy.
Medicina (Kaunas). 2019 Feb 13;55(2):46. doi: 10.3390/medicina55020046.
This study was conducted to evaluate the impact of complementary and alternative medicine (CAM) in patients with irritable bowel syndrome (IBS) as assessed by the Rome IV criteria. Consecutive patients referring for IBS were re-evaluated according to the Rome IV criteria. Demographic features and characteristics potentially associated with the use of CAM were collected. A validated, self-administered, survey questionnaire dealing with CAM and patients' level of knowledge, motivation, perception, and information seeking-behavior toward the use of CAM was analyzed. Multivariate logistic regression analysis was performed in order to identify predictors of CAM use among participants. Among 156 patients claiming IBS, 137 (88%) met the Rome IV criteria, and 62 of them (45%) were CAM users. Biologically based therapy was the most chosen CAM (78%). Significant risk factors (adjusted odds ratio, 95% confidence interval) for the use of CAM were female gender (7.22, 2.31⁻22.51), a higher BMI (1.16, 1.02⁻1.33), and a good knowledge of CAM (4.46, 1.73⁻11.45), while having children was a protective factor (0.25, 0.07⁻0.95). Only 19% of patients used CAM due to medical advice and over half (51%) thought it was a "more natural" approach. Although a minority of patients (16%) had full satisfaction from CAM, 81% of users would repeat the CAM experience for their IBS symptoms. : The widespread use of CAM in IBS, the patients' belief in its safety, and their willingness to re-use it suggest that knowledge of health-care providers and patient education should be improved.
本研究旨在评估按照罗马IV标准评估的补充和替代医学（CAM）对肠易激综合征（IBS）患者的影响。根据罗马IV标准对连续转诊的IBS患者进行重新评估。收集了可能与使用CAM相关的人口统计学特征和特点。分析了一份经过验证的、自我管理的调查问卷，该问卷涉及CAM以及患者对使用CAM的知识水平、动机、认知和信息寻求行为。进行多变量逻辑回归分析以确定参与者中使用CAM的预测因素。在156名自称患有IBS的患者中，137名（88%）符合罗马IV标准，其中62名（45%）是CAM使用者。基于生物的疗法是最常被选择的CAM（78%）。使用CAM的显著风险因素（调整后的优势比，95%置信区间）为女性（7.22，2.31⁻22.51）、较高的体重指数（1.16，1.02⁻1.33）以及对CAM有较好的了解（4.46，1.73⁻11.45），而有孩子是一个保护因素（0.25，0.07⁻0.95）。只有19%的患者因医疗建议而使用CAM，超过一半（51%）的患者认为这是一种“更自然”的方法。尽管少数患者（16%）对CAM完全满意，但81%的使用者会因IBS症状再次使用CAM。IBS患者中CAM的广泛使用、患者对其安全性的信念以及他们再次使用的意愿表明，医疗保健提供者的知识和患者教育应得到改善。
