Department of Ophthalmology, Hyogo College of Medicine, Nishinomiya, Japan.
School of Science and Technology, Kwansei Gakuin University, Sanda, Japan.
Sci Rep. 2019 Feb 20;9(1):2327. doi: 10.1038/s41598-019-38751-z.
We aimed to investigate the possible causes of metamorphopsia for rhegmatogenous retinal detachment (RRD) based on findings of enface optical coherence tomography (OCT). The study was a retrospective, consecutive case series of 33 eyes with macula-off RRD. Metamorphopsia was measured by M-CHARTS and enface OCT images covering a macular area of 6 × 6 mm square obtained at 1, 3, and 6 months postoperatively. Within the outer retinal slabs of enface OCT, multiple lines that looked like folds were delineated in all eyes at month 1, and we succeeded in extracting images of folds by subtracting retinal vessels. We calculated their density by an image-processing technique. The mean M-CHARTS scores were 0.62 ± 0.47 at month 1 and 0.30 ± 0.29 at month 6 (P < 0.001). The fold density was 8.3 ± 4.2 at month 1 and 6.1 ± 3.1 at month 6 (P = 0.0044). The M-CHARTS scores at 6 months were significantly associated with the fold density at 1 month (r = 0.515, P = 0.002). In conclusion, enface OCT visualized the outer retinal folds in eyes that had undergone successful RRD surgery, and a larger number of folds was related to the remaining metamorphopsia.
我们旨在通过光相干断层扫描（OCT）的研究结果，探究孔源性视网膜脱离（RRD）后导致视物变形的可能原因。该研究是一项回顾性的、连续的病例系列研究，纳入了 33 只黄斑裂孔性 RRD 眼。使用 M-CHARTS 量表和术后 1、3 和 6 个月获得的 6×6mm 黄斑区 OCT 进行检查，评估患者的视物变形情况。在 OCT 外视网膜层面，所有患者在术后 1 个月均可见多条类似褶皱的线条，通过减去视网膜血管成功提取出了褶皱图像。我们采用图像处理技术计算其密度。术后 1 个月和 6 个月的平均 M-CHARTS 评分分别为 0.62±0.47 和 0.30±0.29（P<0.001）。术后 1 个月和 6 个月的褶皱密度分别为 8.3±4.2 和 6.1±3.1（P=0.0044）。术后 6 个月的 M-CHARTS 评分与术后 1 个月的褶皱密度显著相关（r=0.515，P=0.002）。总之，OCT 可在 RRD 手术成功的眼中观察到外视网膜褶皱，且褶皱数量越多，残留的视物变形越严重。
