Aaronson N K
Netherlands Cancer Institute, Amsterdam.
Oncology (Williston Park). 1988 May;2(5):69-76, 64.
Efforts have recently been mounted to introduce subjective or "quality of life" parameters as an integral part of the evaluation process in clinical cancer research. While there is no universally accepted definition of the quality of life concept, in oncology it is most often used to describe such aspects of health status as physical symptoms, daily activity level, psychological well-being, and social functioning. The major challenge is to develop measures of the various dimensions of quality of life that, while meeting rigorous standards of validity and reliability, also reflect an appreciation of the practical constraints typically operating in clinical research settings. This overview highlights some of the basic issues surrounding quality of life measurement in oncology.
最近人们致力于将主观或“生活质量”参数引入临床癌症研究评估过程中，作为其不可或缺的一部分。虽然生活质量概念尚无普遍接受的定义，但在肿瘤学中，它最常用于描述健康状况的各个方面，如身体症状、日常活动水平、心理健康和社会功能。主要挑战在于开发生活质量各个维度的测量方法，这些方法既要符合严格的效度和信度标准，又要体现对临床研究环境中通常存在的实际限制的认识。本综述重点介绍了肿瘤学中生活质量测量所涉及的一些基本问题。
