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1
Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis.
Gynecol Oncol. 2019 May;153(2):405-415. doi: 10.1016/j.ygyno.2019.01.020. Epub 2019 Feb 20.
2
Improving fascin inhibitors to block tumor cell migration and metastasis.
Mol Oncol. 2016 Aug;10(7):966-80. doi: 10.1016/j.molonc.2016.03.006. Epub 2016 Apr 1.
3
Fascin is involved in cancer cell invasion and is regulated by stromal factors.
Oncol Rep. 2019 Jan;41(1):465-474. doi: 10.3892/or.2018.6847. Epub 2018 Nov 2.
4
Fas Signaling Promotes Gastric Cancer Metastasis through STAT3-Dependent Upregulation of Fascin.
PLoS One. 2015 May 18;10(5):e0125132. doi: 10.1371/journal.pone.0125132. eCollection 2015.
7
p53 controls colorectal cancer cell invasion by inhibiting the NF-κB-mediated activation of Fascin.
Oncotarget. 2015 Sep 8;6(26):22869-79. doi: 10.18632/oncotarget.5137.
10
The role of fascin in the migration and invasiveness of malignant glioma cells.
Neoplasia. 2008 Feb;10(2):149-59. doi: 10.1593/neo.07909.

引用本文的文献

1
Tropomyosin isoforms encoded by TPM2 control the actin-bundling activity of fascin-1.
Biol Res. 2025 Aug 31;58(1):60. doi: 10.1186/s40659-025-00640-3.
2
Cancer-associated fibroblasts in ovarian cancer: research progress.
Front Oncol. 2025 Mar 4;15:1504762. doi: 10.3389/fonc.2025.1504762. eCollection 2025.
3
The combined tumour-based Fascin/Snail and stromal periostin reveals the effective prognosis prediction in colorectal cancer patients.
PLoS One. 2024 Jun 27;19(6):e0304666. doi: 10.1371/journal.pone.0304666. eCollection 2024.
4
A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation.
Open Biol. 2024 Mar;14(3):230376. doi: 10.1098/rsob.230376. Epub 2024 Mar 20.
6
Fascin-1 in Cancer Cell Metastasis: Old Target-New Insights.
Int J Mol Sci. 2023 Jul 8;24(14):11253. doi: 10.3390/ijms241411253.
7
Roles of Fascin in Dendritic Cells.
Cancers (Basel). 2023 Jul 20;15(14):3691. doi: 10.3390/cancers15143691.
8
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.
Theranostics. 2023 Apr 17;13(7):2368-2383. doi: 10.7150/thno.83938. eCollection 2023.
9
Fascin-1: Updated biological functions and therapeutic implications in cancer biology.
BBA Adv. 2022 May 17;2:100052. doi: 10.1016/j.bbadva.2022.100052. eCollection 2022.

本文引用的文献

1
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.
Cell Metab. 2019 Jan 8;29(1):141-155.e9. doi: 10.1016/j.cmet.2018.08.007. Epub 2018 Aug 30.
2
Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor.
J Mol Biol. 2018 Apr 27;430(9):1324-1335. doi: 10.1016/j.jmb.2018.03.009. Epub 2018 Mar 21.
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Cancer statistics, 2018.
CA Cancer J Clin. 2018 Jan;68(1):7-30. doi: 10.3322/caac.21442. Epub 2018 Jan 4.
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A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth.
SLAS Discov. 2017 Jun;22(5):494-506. doi: 10.1177/2472555216687082. Epub 2017 Jan 31.
6
Improving fascin inhibitors to block tumor cell migration and metastasis.
Mol Oncol. 2016 Aug;10(7):966-80. doi: 10.1016/j.molonc.2016.03.006. Epub 2016 Apr 1.
8
Rho GTPase signalling in cell migration.
Curr Opin Cell Biol. 2015 Oct;36:103-12. doi: 10.1016/j.ceb.2015.08.005. Epub 2015 Sep 10.
10
Microenvironment-induced downregulation of miR-193b drives ovarian cancer metastasis.
Oncogene. 2015 Nov 26;34(48):5923-32. doi: 10.1038/onc.2015.43. Epub 2015 Mar 23.

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