Bristol Eye Hospital, Bristol, UK.
Ophthalmology, Princess Alexandra Hospital, Woolloongabba, Brisbane, Australia.
Br J Ophthalmol. 2019 Dec;103(12):1700-1703. doi: 10.1136/bjophthalmol-2018-313385. Epub 2019 Feb 23.
To report 15 cases of intraocular lens (IOL) calcification following intraocular surgery and to identify common risk factors.
A retrospective case review of patients with IOL calcification reported from the Royal Victorian Eye and Ear Hospital, Melbourne, Australia, and six surgeons in private practice in the Australian states of Victoria, New South Wales and Queensland.
15 cases of IOL calcification were identified. Eight cases were in hydrophilic acrylic IOLs and seven in hydrophilic acrylic IOLs with hydrophobic surface properties. Five cases occurred following intraocular injection of gas during endothelial keratoplasties. Two cases occurred following pars plana vitrectomy where gas was used. The remaining eight cases did not involve the injection of any intraocular gas; six cases were following trabeculectomy surgery, and two cases were after insertion of a 'piggyback' sulcus IOL. In each case, the calcification had a characteristic pattern, being centrally placed in the pupillary zone, mainly affecting the anterior lens surface.
The aetiology of IOL calcification is not fully understood, although there are known risk factors such as using hydrophilic acrylic materials and the use of intraocular gas. Surgical consideration of a patient's ocular comorbidities before IOL implantation is an important tool to mitigate some of this risk.
报告 15 例眼内手术后的人工晶状体（IOL）钙化病例，并确定常见的危险因素。
对来自澳大利亚墨尔本皇家维多利亚眼耳医院和维多利亚州、新南威尔士州和昆士兰州的六名私人执业外科医生报告的 IOL 钙化患者进行回顾性病例分析。
共发现 15 例 IOL 钙化病例。8 例发生在亲水性丙烯酸酯 IOL 中，7 例发生在亲水性丙烯酸酯 IOL 与疏水性表面特性。5 例发生在穿透性角膜内皮移植术中眼内注射气体后。2 例发生在使用气体的玻璃体切除术之后。其余 8 例未涉及任何眼内气体注射；6 例发生在小梁切除术之后，2 例发生在植入“附加”巩膜沟 IOL 之后。在每种情况下，钙化都具有特征性模式，位于瞳孔区中央，主要影响前晶状体表面。
尽管已知存在使用亲水性丙烯酸材料和眼内气体等危险因素，但 IOL 钙化的确切病因仍不完全清楚。在植入 IOL 之前，根据患者的眼部合并症对手术进行考虑，是减轻部分风险的重要手段。
