精索静脉曲张手术后补充维生素E - 硒 - 叶酸对改善精子参数的作用：一项随机临床试验。

The role of Vitamin E - Selenium - Folic Acid Supplementation in Improving Sperm Parameters After Varicocelectomy: A Randomized Clinical Trial.

作者信息

Ardestani Zadeh Arash, Arab Davood, Kia Naim Sadat, Heshmati Sajjad, Amirkhalili Seyed Nilofar

机构信息

Clinical Research Development Center, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran.

Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.

出版信息

Urol J. 2019 Oct 21;16(5):495-500. doi: 10.22037/uj.v0i0.4653.

DOI:10.22037/uj.v0i0.4653

PMID:30798568

Abstract

PURPOSE

In this study, we aimed to evaluate the effects of antioxidants including Vitamin E-Selenium-Folic acid (Vit E -Se- FA) on semen parameters following varicocelectomy (VCT).

MATERIALS AND METHODS

Sixty patients from 64 infertile male patients diagnosed with varicocele (VC) who un-derwent sub-inguinal VCT were included in the study. Following sub-inguinal VCT, the patients were randomized into two groups: 30 receiving Vit E-Se-FA supplementation for six months, and 30 as the control group with supplemental treatment. The post-operative semen parameters of Vit E-Se-FA receiving group were compared with control group at the end of experiment. The sperm count, percentage of motile and abnormal sperms were considered.

RESULTS

There were statistically significant differences in terms of count (P = .031) and motility (P = .01) of sperm after six months of receiving Vit E-Se-FA supplementation comparing with control group.

CONCLUSION

Vit E-Se-FA supplementation can improve sperm parameters (count and motility of sperm) after VCT.

摘要

目的

在本研究中，我们旨在评估抗氧化剂，包括维生素E-硒-叶酸（Vit E -Se- FA）对精索静脉曲张切除术（VCT）后精液参数的影响。

材料与方法

本研究纳入了64例诊断为精索静脉曲张（VC）并接受腹股沟下VCT的男性不育患者中的60例。腹股沟下VCT术后，患者被随机分为两组：30例接受Vit E-Se-FA补充剂治疗6个月，30例作为对照组接受补充治疗。实验结束时，将接受Vit E-Se-FA治疗组的术后精液参数与对照组进行比较。考虑精子数量、活动精子百分比和异常精子百分比。