Munro A D
Psychopharmacology (Berl). 1986;88(1):124-8. doi: 10.1007/BF00310527.
Apomorphine, d-amphetamine, chlorpromazine and dopamine, added to the aquarium water, were tested for their effects on the aggressive responses of isolated fish to mirrors and to models, compared with the responses of the same fish as non-treated controls tested at the start of, in the middle, and at the end of the experiment (Experiment 1). The effects of d-amphetamine administered by intracranial injection were also evaluated for responses to mirror presentations (Experiment 2). The three sets of controls in Experiment 1 indicate that the responses of the fish apparently changed over the 32-day experiment: they became more aggressive to mirrors whilst reacting less to models. Dopamine had no behavioural effect. Immersion in either apomorphine or d-amphetamine resulted in increased swimming activity, accompanied by apparent behavioural stereotypy. Immersion in apomorphine (Experiment 1) and intracranial injections of d-amphetamine (Experiment 2) also resulted in reduced aggression. Likewise, chlorpromazine also reduced some measures of overt aggression, whilst the appearance of other behaviours suggested that there is also an increased tendency to withdraw from the stimulus. It is concluded that the dopaminergic system plays an important role in the regulation of aggressive behaviour in this cichlid fish.
将阿扑吗啡、右旋苯丙胺、氯丙嗪和多巴胺添加到水族箱水中，测试它们对隔离鱼对镜子和模型的攻击反应的影响，并与在实验开始、中间和结束时作为未处理对照的同一条鱼的反应进行比较（实验1）。还评估了通过颅内注射给予右旋苯丙胺对镜子呈现反应的影响（实验2）。实验1中的三组对照表明，在32天的实验过程中，鱼的反应明显发生了变化：它们对镜子变得更具攻击性，而对模型的反应则减弱。多巴胺没有行为影响。浸泡在阿扑吗啡或右旋苯丙胺中会导致游泳活动增加，并伴有明显的行为刻板症。浸泡在阿扑吗啡中（实验1）和颅内注射右旋苯丙胺（实验2）也会导致攻击性降低。同样，氯丙嗪也减少了一些明显攻击行为的指标，而其他行为的出现表明从刺激中退缩的倾向也增加了。得出的结论是，多巴胺能系统在这种丽鱼科鱼类攻击行为的调节中起重要作用。
