Chokhachi Zadeh Moghadam Nastaran, Seraj Bahman, Chiniforush Nasim, Ghadimi Sara
University of California Los Angeles - UCLA, School of Dentistry, Department of Hospital Dentistry, Los Angeles, California, USA.
Dental Research Center, Dentistry Research Institute and Department of Pediatric Dentistry, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
J Lasers Med Sci. 2018 Summer;9(3):177-182. doi: 10.15171/jlms.2018.32. Epub 2018 Jul 28.
Investigations have demonstrated that fluoride is an essential element in preventive dentistry. However, there are still controversies about the preventive effects of various kinds of laser. The aim of this study was to examine the effect of diode laser irradiation (810 nm) with or without fluoride therapy in the prevention of deciduous enamel demineralization. Sixty deciduous molar crowns were randomly assigned to 6 groups: C: received no treatment; F: fluoride varnish application; 2L: 2 times diode laser irradiation; 4L: 4 times diode laser irradiation; F2L: 2 times laser irradiation over fluoride varnish; F4L: 4 times laser irradiation over fluoride varnish. Teeth in all groups were subjected to a pH-cycling process to produce artificial caries-like lesions. The analysis of variance (ANOVA) of microhardness values indicated a significant great effect for laser, fluoride, and the interaction of laser- fluoride on reducing the final microhardness value (<0.001). However, the 2L group was an exception. Despite the 4L group, it did not show a significant prevention of enamel microhardness loss (=0.125). These 2 groups exhibited different effects in the absence of fluoride ( =0.05) while in the presence of the fluoride varnish, no statistically significant difference was observed between them ( =0.257). Moreover, no statistically significant difference was observed between the laser-fluoride combination group and the fluoride group ( =0.133, =0.926). Our results suggest that fluoride varnish, diode laser, and their combination decrease the loss of the enamel microhardness value and potentially prevent deciduous enamel demineralization. However, the combination of laser and fluoride was not more effective than fluoride.
研究表明，氟化物是预防牙科中的一种必需元素。然而，关于各种激光的预防效果仍存在争议。本研究的目的是检验810nm二极管激光照射联合或不联合氟化物治疗对预防乳牙釉质脱矿的效果。将60颗乳牙牙冠随机分为6组：C组：未接受治疗；F组：涂抹氟化物 varnish；2L组：二极管激光照射2次；4L组：二极管激光照射4次；F2L组：在氟化物 varnish上进行2次激光照射；F4L组：在氟化物 varnish上进行4次激光照射。所有组的牙齿都经过pH循环过程以产生人工龋样病变。显微硬度值的方差分析（ANOVA）表明，激光、氟化物以及激光 - 氟化物相互作用对降低最终显微硬度值有显著的巨大影响（<0.001）。然而，2L组是个例外。与4L组不同，它未显示出对釉质显微硬度损失的显著预防作用（=0.125）。这两组在无氟化物时表现出不同的效果（=0.05），而在有氟化物 varnish存在时，它们之间未观察到统计学上的显著差异（=0.257）。此外，激光 - 氟化物联合组与氟化物组之间未观察到统计学上的显著差异（=0.133，=0.926）。我们的结果表明，氟化物 varnish、二极管激光及其联合使用可降低釉质显微硬度值的损失，并有可能预防乳牙釉质脱矿。然而，激光和氟化物的联合使用并不比氟化物更有效。
