Croome Kristopher P, Lee David D, Taner C Burcin
Department of Transplant, Mayo Clinic Florida, Jacksonville, FL.
Liver Transpl. 2019 Mar;25(3):488-499. doi: 10.1002/lt.25408.
The frequency at which steatotic deceased donor liver grafts are encountered will likely continue to increase. Utilization of liver grafts with moderate-to-severe steatosis for liver transplantation (LT) has been previously shown to be associated with increased rates of primary nonfunction and decreased recipient survival. In order to better inform clinical decision making and guide future research, critical evaluation of the literature on donor liver steatosis and posttransplantation outcome is needed. This literature review aims to provide the "skinny" on using deceased donor steatotic livers for LT.
脂肪变性的已故供体肝移植的发生率可能会持续上升。先前的研究表明，使用中度至重度脂肪变性的肝移植进行肝移植（LT）与原发性无功能发生率增加和受体生存率降低有关。为了更好地为临床决策提供信息并指导未来的研究，需要对有关供体肝脂肪变性和移植后结果的文献进行批判性评估。这篇文献综述旨在提供关于使用已故供体脂肪变性肝脏进行肝移植的“内幕”信息。
