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日本靶向放射性核素治疗的发展活动。

Activities for the Development of Targeted Radionuclide Therapy in Japan.

作者信息

Kinuya Seigo

机构信息

Department of Nuclear Medicine, Kanazawa University Hospital, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641 Japan.

出版信息

Nucl Med Mol Imaging. 2019 Feb;53(1):35-37. doi: 10.1007/s13139-018-0563-4. Epub 2018 Dec 15.

DOI:10.1007/s13139-018-0563-4
PMID:30828398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6377573/
Abstract

Targeted radionuclide therapy (TRT) is unique because of its efficacy and its theranostic feature in the era of precision medicine. So far, introduction of new TRT has not been going well in Japan due to several reasons including strict regulations, shortage of facilities for TRT, and insufficient reimbursement for TRT in clinic. Japanese community had several strategies to develop TRT in these 10 years, including the establishment of the National Conference for Nuclear Medicine Theranostics in which physicians, scientists, patients, people supporting patients, and industrial people gather. To promote TRT with supports from the government, the preparatory committee for the establishment of Japan Foundation of Medical Isotope Development (JAFMID) was launched. I would like to call TRT "Precision Nuclear Medicine." When we can add genomic information here, we can put it to new stage of cancer therapy. It is time for us.

摘要

靶向放射性核素治疗(TRT)因其疗效以及在精准医学时代的诊疗一体化特性而独具特色。到目前为止,由于包括严格的监管、TRT设施短缺以及临床中TRT报销不足等多种原因,新型TRT在日本的引入进展并不顺利。在过去十年里,日本各界采取了多种策略来发展TRT,包括成立核医学诊疗全国会议,医生、科学家、患者、患者支持者以及产业界人士齐聚于此。为在政府支持下推动TRT发展,日本医学同位素开发基金会(JAFMID)成立筹备委员会启动。我想将TRT称为“精准核医学”。当我们在此加入基因组信息时,就能将癌症治疗推向新的阶段。是我们行动的时候了。

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Ann Nucl Med. 2019 Mar;33(3):211-221. doi: 10.1007/s12149-018-1317-1. Epub 2018 Nov 27.
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Phase I/IIa PET imaging study with zirconium labeled anti-PSMA minibody for urological malignancies.用锆标记的抗前列腺特异性膜抗原(PSMA)微型抗体对泌尿生殖系统恶性肿瘤进行的I/IIa期正电子发射断层扫描(PET)成像研究。
Ann Nucl Med. 2019 Feb;33(2):119-127. doi: 10.1007/s12149-018-1312-6. Epub 2018 Nov 7.
3
Clinical feasibility of early scanning after administration of Ga-DOTATOC.给予Ga-DOTATOC后早期扫描的临床可行性
Ann Nucl Med. 2019 Jan;33(1):55-60. doi: 10.1007/s12149-018-1304-6. Epub 2018 Sep 20.
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Molecular imaging reporting and data systems (MI-RADS): a generalizable framework for targeted radiotracers with theranostic implications.分子影像报告与数据系统(MI-RADS):具有治疗诊断意义的靶向放射性示踪剂的通用框架。
Ann Nucl Med. 2018 Oct;32(8):512-522. doi: 10.1007/s12149-018-1291-7. Epub 2018 Aug 14.
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CXCR4-directed theranostics in oncology and inflammation.肿瘤学与炎症中靶向CXCR4的诊疗一体化
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Ann Nucl Med. 2018 Oct;32(8):568-572. doi: 10.1007/s12149-018-1276-6. Epub 2018 Jul 26.
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Ann Nucl Med. 2018 Aug;32(7):499-502. doi: 10.1007/s12149-018-1264-x. Epub 2018 May 23.
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