Hoffer Michael E, Levin Bonnie E, Snapp Hillary, Buskirk James, Balaban Carey
Department of Otolaryngology University of Miami Miller School of Medicine Miami Florida.
Department of Neurological Surgery University of Miami Miller School of Medicine Miami Florida.
Laryngoscope Investig Otolaryngol. 2018 Dec 12;4(1):124-131. doi: 10.1002/lio2.231. eCollection 2019 Feb.
In the Autumn of 2016, diplomatic personnel residing in Havana began to present with symptoms of dizziness, ear pain, and tinnitus that emerged after perception of high frequency noise and/or a pressure sensation. Understanding the acute symptoms of this disorder is important for better defining the disorder and developing optimal diagnostic, preventive, and treatment algorithms.
To define the presenting symptoms in a cohort of patients in the acute time period after perceiving a noise/pressure exposure in Havana.
DESIGN/SETTINGS/PARTICIPANTS: Review of 25 symptomatic individuals who reported a localized sensation of noise/pressure and 10 asymptomatic individuals (roommates of those affected) who did not experience the sound/pressure.
Immediately after the exposure, the majority of individuals reported intense ear pain in one or both ears and experienced tinnitus. All of the individuals noticed unsteadiness and features of cognitive impairment. On presentation to our center, dizziness (92%) and cognitive complaints (56%) were the most common symptoms. Formal testing revealed that 100% of individuals had an otolithic abnormality and evidence of cognitive dysfunction.
This study focuses on the acute presentation of a phenomenon in which symptoms emerge after perception of a localized noise/pressure and in which the acute symptomology includes the universal nature of vestibular injuries and select cognitive deficits. The findings presented in this acute group of patients begin to provide a better picture of the initial injury pattern seen after this exposure and may allow for more accurate diagnosis of this disorder in future cases.
Retrospective review.
2016年秋季，居住在哈瓦那的外交人员开始出现头晕、耳痛和耳鸣症状，这些症状在感知高频噪声和/或压力感之后出现。了解这种疾病的急性症状对于更好地定义该疾病以及制定最佳诊断、预防和治疗方案很重要。
确定哈瓦那一批在感知噪声/压力暴露后的急性期患者所表现出的症状。
设计/地点/参与者：对25名报告有局部噪声/压力感的有症状个体以及10名未经历该声音/压力的无症状个体（受影响者的室友）进行回顾性研究。
暴露后立即出现的情况是，大多数个体报告一侧或双侧耳朵剧烈疼痛并伴有耳鸣。所有个体都注意到了身体不稳和认知障碍特征。到我们中心就诊时，头晕（92%）和认知方面的主诉（56%）是最常见的症状。正式检查显示，100%的个体存在耳石异常和认知功能障碍的证据。
本研究聚焦于一种现象的急性期表现，即症状在感知局部噪声/压力后出现，且急性症状包括前庭损伤的普遍特征和特定的认知缺陷。这组急性患者的研究结果开始为这种暴露后所见的初始损伤模式提供更清晰的情况，并可能有助于未来病例中对该疾病进行更准确的诊断。
回顾性研究。
