Department of Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
Department of Pathology, Northwestern Feinberg School of Medicine, Chicago, Illinois.
J Neuropathol Exp Neurol. 2019 Apr 1;78(4):294-296. doi: 10.1093/jnen/nlz012.
World Health Organization (WHO) central nervous system tumor classification represents the primary source of updates on diagnostic classes, grades, and criteria. However, recent and ongoing advances in molecular pathogenesis warrant more rapid integration into clinical practice between WHO updates. To accomplish this, the consortium to inform molecular and practical approaches to CNS tumor taxonomy-not official WHO (cIMPACT-NOW) was established in 2016. Since then, cIMPACT-NOW has convened 3 separate working committees to address classification and grading questions and challenges. This review covers the progress that these working committees have made on their specific topics.
世界卫生组织（WHO）中枢神经系统肿瘤分类代表了诊断类别、分级和标准的主要更新来源。然而，分子发病机制方面的最新进展和持续进展要求在 WHO 更新之间更快速地将其纳入临床实践。为了实现这一目标，于 2016 年成立了旨在为中枢神经系统肿瘤分类提供分子和实用方法信息的联盟-非官方 WHO（cIMPACT-NOW）。自那时以来，cIMPACT-NOW 已召集了 3 个独立的工作组来解决分类和分级问题和挑战。本综述涵盖了这些工作组在其特定主题上取得的进展。
