Hoffmann M L, Zrenner E, Langhof H J
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Jun 19;206(4):237-45. doi: 10.1007/BF02387335.
The electroretinogram (ERG) was recorded in 10 normal subjects under scotopic and photopic conditions with the pupil of one eye constricted and that of the other eye dilated. The human iris, being displaced from the nodal point of the eye, acts not only as an aperture, regulating the retinal illumination, but also as a field stop, limiting the visual angle, especially for large object fields, as in Ganzfeld illumination. This double effect of a constricted pupil clearly influences the Ganzfeld ERG, not only shifting the intensity response functions to higher luminances but also diminishing the maximal responses. Control experiments with smaller test fields, which are less affected by the pupillary field-stop properties, reveal no diminution of the scotopic b-wave amplitudes. Implicit time functions, being nearly independent of the number of receptors stimulated, can be matched by taking into account the pupillary diameter and calculating the actual retinal illumination (Troland). Amplitudes, being highly affected by a decrease of responding neurons due to the angle-limiting field-stop character of the pupil, cannot be matched with regard to the pupillary diameter. This effect is most noticeable in Ganzfeld illumination for the scotopic b-wave, generated mainly by neurons of the peripheral retina, and has less effect on the photopic responses that are generated more centrally.
在暗视和明视条件下,对10名正常受试者进行视网膜电图(ERG)记录,其中一只眼睛的瞳孔收缩,另一只眼睛的瞳孔扩张。人眼的虹膜偏离眼球的节点,不仅作为一个孔径调节视网膜光照,还作为一个视场光阑限制视角,特别是对于大视野,如全视野照明。收缩瞳孔的这种双重作用明显影响全视野ERG,不仅将强度响应函数向更高亮度移动,还减小了最大响应。使用较小测试视野的对照实验(受瞳孔视场光阑特性影响较小)显示暗视b波振幅没有减小。潜伏期函数几乎与受刺激的感受器数量无关,通过考虑瞳孔直径并计算实际视网膜光照(特罗兰)可以进行匹配。振幅受瞳孔角度限制视场光阑特性导致的响应神经元减少的影响很大,无法根据瞳孔直径进行匹配。这种效应在全视野照明中对主要由周边视网膜神经元产生的暗视b波最为明显,而对更多由中央产生的明视反应影响较小。