源自深海真菌SCSIO z053的新型二苯并二氧杂环己酮和吡喃-3,5-二酮衍生物
New dibenzodioxocinone and pyran-3,5-dione derivatives from the deep-sea-derived fungus SCSIO z053.
作者信息
Dasanayaka S A H K, Nong Xu-Hua, Liang Xiao, Liang Jian-Qiu, Amin Muhammad, Qi Shu-Hua
机构信息
CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
出版信息
J Asian Nat Prod Res. 2020 Apr;22(4):338-345. doi: 10.1080/10286020.2019.1575819. Epub 2019 Mar 5.
A new isopentylated dibenzodioxocinone, canescenin A (), and a new isopentylated pyran-3,5-dione derivative, canescenin B (), were isolated from an extract of the deep-sea-derived fungus SCSIO z053. Their structures were elucidated by spectroscopic analysis. It was rare to obtain pyran-3,5-dione derivatives from nature. Antibacterial, cytotoxic, and antiviral activities of and were also evaluated.
从深海来源的真菌SCSIO z053的提取物中分离出一种新的异戊烯基化二苯并二恶英酮——毛钩藤宁A（）和一种新的异戊烯基化吡喃-3,5-二酮衍生物——毛钩藤宁B（）。通过光谱分析阐明了它们的结构。从自然界中获得吡喃-3,5-二酮衍生物是很罕见的。还评估了和的抗菌、细胞毒性和抗病毒活性。
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