Ferreira Josiel Borges, Sotomaior Cristina Santos, Bezerra Ana Carla Diógenes Suassuna, da Silva Wilma Emanuela, Leite Jacinara Hody Gurgel Morais, de Sousa José Ernandes Rufino, de Fátima França Biz Jesséa, Façanha Débora Andréa Evangelista
Laboratory of Adaptive Physiology and Genetic Resources, Department of Animal Science, Federal University of Semiarid (UFERSA), Rodovia BR 110, Km 47, Mossoró, Rio Grande do Norte, 59625-900, Brazil.
Animal Science Program (PPGCA), UFERSA, Mossoró, Rio Grande do Norte, 59625-900, Brazil.
Trop Anim Health Prod. 2019 Jul;51(6):1767-1771. doi: 10.1007/s11250-019-01861-x. Epub 2019 Mar 5.
The aim of this research was to evaluate the sensitivity and specificity of the FAMACHA (F) system in Morada Nova ewes. The conjunctivae of 562 ewes were evaluated using the F system. Packed cell volume (PCV) served as the gold standard for clinical F evaluation. To calculate the sensitivity and specificity of the F system, different criteria were adopted: animals classified as (I) F 4 and 5 or (II) 3, 4, and 5 were considered to be anemic and animals classified as (I) F 1, 2, and 3, or (II) 1 and 2 were considered to be non-anemic. Three standard values of PCV, namely, ≤ 19%, ≤ 18%, or ≤ 15%, were used to confirm anemia. The percentage of correct treatments was always high when the F values 4 and 5 were used as criteria for positive tests. For all the PCV cut-off values, more animals were classified as false positives when evaluated using F 3, 4, and 5 as criteria for a positive test and more true negative animals when evaluated using only F 4 and 5 as criteria for a positive test. For both sets of criteria for the positive tests, few animals were classified as false negatives and true positives. Eliminating the classification of F 3 as anemic decreased the sensitivity and increased the specificity for all the PCV cut-off values for the ewes. The F system can be used as a reliable alternative to reduce selection pressure for anthelmintics in relation to routine non-selective blanket treatment for worm control in the Morada Nova ewes.
本研究的目的是评估FAMACHA（F）系统在莫拉达诺瓦母羊中的敏感性和特异性。使用F系统对562只母羊的结膜进行了评估。血细胞比容（PCV）作为临床F评估的金标准。为了计算F系统的敏感性和特异性，采用了不同的标准：被归类为（I）F 4和5或（II）3、4和5的动物被视为贫血，被归类为（I）F 1、2和3或（II）1和2的动物被视为非贫血。使用三个PCV标准值，即≤19%、≤18%或≤15%来确认贫血。当将F值4和5用作阳性检测标准时，正确治疗的百分比始终很高。对于所有PCV临界值，以F 3、4和5作为阳性检测标准进行评估时，更多动物被归类为假阳性，而仅以F 4和5作为阳性检测标准进行评估时，更多动物为真阴性。对于两组阳性检测标准，很少有动物被归类为假阴性和真阳性。将F 3归类为贫血的分类排除后，母羊所有PCV临界值的敏感性降低，特异性增加。与莫拉达诺瓦母羊蠕虫控制的常规非选择性全面治疗相比，F系统可作为一种可靠的替代方法，以降低驱虫药的选择压力。
