Marsh Jeffrey F, Jorgensen Steven M, Rundle David S, Vercnocke Andrew J, Leng Shuai, Butler Philip H, McCollough Cynthia H, Ritman Erik L
Mayo Clinic, Department of Radiology, Rochester, Minnesota, United States.
JairiNovus Technologies Ltd., Butler, Pennsylvania, United States.
J Med Imaging (Bellingham). 2018 Oct;5(4):043503. doi: 10.1117/1.JMI.5.4.043503. Epub 2018 Dec 4.
We assess the performance of a cadmium zinc telluride (CZT)-based Medipix3RX energy-resolving and photon-counting x-ray detector as a candidate for spectral microcomputed tomography (micro-CT) imaging. It features an array of , pixels, each with four simultaneous threshold counters that utilize real-time charge summing. Each pixel's response is assessed by imaging with a range of incident x-ray intensities and detector integration times. Energy-related assessments are made by exposing the detector to the emission from an I-125 radioisotope brachytherapy seed. Long-term stability is assessed by repeating identical exposures over the course of 1 h. The high yield of properly functioning pixels (98.8%), long-term stability (linear regression of whole-chip response over 1 h of acquisitions: ; standard deviation: 3.7 counts), and energy resolution [2.5 keV full-width half-maximum (FWHM) (single pixel), 3.7 keV FWHM (across the full image)] make this device suitable for spectral micro-CT.
我们评估了一款基于碲锌镉（CZT）的Medipix3RX能量分辨型光子计数X射线探测器作为光谱显微计算机断层扫描（显微CT）成像候选设备的性能。它具有一个由 个像素组成的阵列，每个像素有四个同时工作的阈值计数器，采用实时电荷求和技术。通过用一系列不同的入射X射线强度和探测器积分时间进行成像，来评估每个像素的响应。通过将探测器暴露于I - 125放射性同位素近距离治疗种子源的发射中来进行与能量相关的评估。通过在1小时内重复相同的曝光来评估长期稳定性。正常工作像素的高产率（98.8%）、长期稳定性（在1小时采集过程中全芯片响应的线性回归： ；标准差：3.7计数）以及能量分辨率[2.5 keV半高宽（FWHM）（单个像素），3.7 keV FWHM（整个图像）]使得该设备适用于光谱显微CT。
