Fransen L, Nsanze H, Klauss V, Van der Stuyft P, D'Costa L, Brunham R C, Piot P
J Infect Dis. 1986 May;153(5):862-9. doi: 10.1093/infdis/153.5.862.
Among 149 consecutive infants with ophthalmia neonatorum in Nairobi, Neisseria gonorrhoeae was recovered from 43%, Chlamydia trachomatis from 13%, and both microorganisms from 4%. Three of five isolates of C. trachomatis belonged to trachoma serovars. The sensitivity and specificity of a gram-stained smear for the diagnosis of gonococcal conjunctivitis were 86% and 90%, respectively. Patients with gonococcal conjunctivitis had more purulent discharge, a higher clinical severity score, and a younger age at onset of disease. Corneal epithelial edema with superficial keratitis was present in four (16%) of 25 patients with gonococcal conjunctivitis but in none of 22 other patients (P = .07). N. gonorrhoeae or C. trachomatis was isolated from the pharynx in 11 (15%) and six (23%) cases, respectively. Oropharyngeal gonococcal infection was associated with coughing (P = .007).
在内罗毕连续收治的149例新生儿眼炎患儿中，43%分离出淋病奈瑟菌，13%分离出沙眼衣原体，4%同时分离出这两种微生物。5株沙眼衣原体分离株中有3株属于沙眼血清型。革兰氏染色涂片诊断淋菌性结膜炎的敏感性和特异性分别为86%和90%。淋菌性结膜炎患者的脓性分泌物更多、临床严重程度评分更高且发病年龄更小。25例淋菌性结膜炎患者中有4例（16%）出现角膜上皮水肿伴浅层角膜炎，而其他22例患者均未出现（P = 0.07）。分别在11例（15%）和6例（23%）病例的咽部分离出淋病奈瑟菌或沙眼衣原体。口咽部淋病奈瑟菌感染与咳嗽有关（P = 0.007）。
