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宫颈癌女性的健康相关生活质量

Health-related Quality of Life in Women with Cervical Cancer.

作者信息

Dos Santos Larissa Nascimento, Castaneda Luciana, de Aguiar Suzana Sales, Thuler Luiz Claudio Santos, Koifman Rosalina Jorge, Bergmann Anke

机构信息

Instituto Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Instituto Nacional de Câncer, Rio de Janeiro, RJ, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2019 Apr;41(4):242-248. doi: 10.1055/s-0039-1683355. Epub 2019 Mar 7.

DOI:10.1055/s-0039-1683355
PMID:30847876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10309270/
Abstract

OBJECTIVE

To analyze the factors associated with health-related quality of life (HRQoL) in women with cervical cancer (CC) in a single center in Rio de Janeiro, state of Rio de Janeiro, Brazil.

METHODS

A cross-sectional study in women with a diagnosis of CC followed-up in the gynecology outpatient clinic of the Hospital do Câncer II (HCII, in the Portuguese acronym) of the Instituto Nacional de Câncer (INCA, in the Portuguese acronym). The data were collected from March to August 2015. Women with palliative care, communication/cognition difficulty, undergoing simultaneous treatment for other types of cancer, or undergoing chemotherapy and/or radiation therapy were excluded. For the evaluation of the HRQoL, a specific questionnaire for women with CC was used (Functional Assessment of Cancer Therapy - Cervix Cancer [FACT-Cx]). The total score of the questionnaire ranges from 0 to 168, with higher scores indicating a better HRQoL.

RESULTS

A total of 115 women were included in the present study, with a mean age of 52.64 years old (standard deviation [SD] = 12.13). The domains of emotional (16.61; SD = 4.55) and functional well-being (17.63; SD = 6.15) were those which presented the worst scores. The factors that had an association with better HRQoL in women with CC were having a current occupation, a longer time since the treatment and diagnosis, and women who had undergone hysterectomy.

CONCLUSION

Considering the domains of HRQoL of the women treated for cervical cancer, a better score was observed in the domains of physical and social/family well-being. For most domains, better scores were found between those with a current occupation, with a longer time after the diagnosis and treatment, and among those who had undergone a hysterectomy.

摘要

目的

分析巴西里约热内卢州里约热内卢市某单一中心宫颈癌(CC)女性患者健康相关生活质量(HRQoL)的相关因素。

方法

对在国立癌症研究所(INCA,葡萄牙语首字母缩写)的癌症医院II(HCII,葡萄牙语首字母缩写)妇科门诊随访的确诊为CC的女性进行横断面研究。数据收集于2015年3月至8月。排除接受姑息治疗、存在沟通/认知困难、同时接受其他类型癌症治疗或正在接受化疗和/或放疗的女性。为评估HRQoL,使用了针对CC女性的特定问卷(癌症治疗功能评估 - 宫颈癌[FACT-Cx])。问卷总分范围为0至168分,分数越高表明HRQoL越好。

结果

本研究共纳入115名女性,平均年龄为52.64岁(标准差[SD]=12.13)。情感领域(16.61;SD=4.55)和功能幸福感领域(17.63;SD=6.15)得分最差。与CC女性更好的HRQoL相关的因素包括目前有工作、治疗和诊断后时间较长以及接受过子宫切除术的女性。

结论

考虑到接受宫颈癌治疗女性的HRQoL领域,在身体和社会/家庭幸福感领域观察到更好的得分。对于大多数领域,目前有工作、诊断和治疗后时间较长以及接受过子宫切除术的女性得分更高。

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