Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Brain Res Bull. 2019 May;148:10-17. doi: 10.1016/j.brainresbull.2019.02.015. Epub 2019 Mar 6.
Despite the prevalence of stroke, therapies to augment recovery remain limited. Here we focus on the use of conductive polymers for cell delivery, drug release, and electrical stimulation to optimize the post-stroke environment for neural recovery. Conductive polymers and their interactions with in vitro and in vivo neural systems are explored. The ability to continuously modify the neural environment utilizing conductive polymers provides applications in directing stem cell differentiation and increasing neural repair. This exciting class of polymers offers new approaches to optimizing the post-stroke brain to improve functional recovery.
尽管中风很常见，但增强恢复的治疗方法仍然有限。在这里，我们专注于使用导电聚合物进行细胞输送、药物释放和电刺激，以优化中风后的神经恢复环境。探索了导电聚合物及其与体外和体内神经系统的相互作用。利用导电聚合物持续改变神经环境的能力为指导干细胞分化和增加神经修复提供了应用。这种令人兴奋的聚合物为优化中风后的大脑以改善功能恢复提供了新的方法。
