Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic
Unit of Microbiology and Clinical Microbiology, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Antimicrob Agents Chemother. 2019 Apr 25;63(5). doi: 10.1128/AAC.02609-18. Print 2019 May.
We report two KPC-producing isolates from unrelated patients. In one case, was harbored on a novel variant of a Tn transposon of an IncN plasmid conjugated together with a coresident IncA plasmid, whereas in the other one, was on a Tn transposon located on an IncX3-IncA self-conjugative plasmid fusion. The interplay among plasmids carrying and the coresident IncA plasmids offers new information on plasmids coresident within clinically relevant enterobacteria.
我们报道了两株来自无关患者的产 KPC 分离株。在一个病例中, 位于一个 IncN 质粒的 Tn 转座子的新型变体上,与一个共存的 IncA 质粒一起被携带,而在另一个病例中, 位于位于 IncX3-IncA 自我接合质粒融合物上的 Tn 转座子上。携带 和共存的 IncA 质粒之间的相互作用提供了有关临床相关肠杆菌内共存质粒的新信息。