Center for Visual Information Technology, International Institute of Information Technology (IIIT), Hyderabad, Telangana, India.
Center for Visual Information Technology, International Institute of Information Technology (IIIT), Hyderabad, Telangana; Probabilistic Vision Group, Centre for Intelligent Machines, Department of electrical and Computer Engineering, McGill University, Montreal, QC, Canada.
Neurol India. 2019 Jan-Feb;67(1):229-234. doi: 10.4103/0028-3886.253639.
A brain magnetic resonanace imaging (MRI) atlas plays an important role in many neuroimage analysis tasks as it provides an atlas with a standard coordinate system which is needed for spatial normalization of a brain MRI. Ideally, this atlas should be as near to the average brain of the population being studied as possible.
The aim of this study is to construct and validate the Indian brain MRI atlas of young Indian population and the corresponding structure probability maps.
This was a population-specific atlas generation and validation process.
100 young healthy adults (M/F = 50/50), aged 21-30 years, were recruited for the study. Three different 1.5-T scanners were used for image acquisition. The atlas and structure maps were created using nonrigid groupwise registration and label-transfer techniques.
The generated atlas was compared against other atlases to study the population-specific trends.
The atlas-based comparison indicated a signifi cant difference between the global size of Indian and Caucasian brains. This difference was noteworthy for all three global measures, namely, length, width, and height. Such a comparison with the Chinese and Korean brain templates indicate all 3 to be comparable in length but signifi cantly different (smaller) in terms of height and width.
The findings confirm that there is significant difference in brain morphology between Indian, Chinese, and Caucasian populations.
大脑磁共振成像（MRI）图谱在许多神经影像分析任务中起着重要作用，因为它提供了一个具有标准坐标系的图谱，这是大脑 MRI 空间归一化所必需的。理想情况下，该图谱应尽可能接近所研究人群的平均大脑。
本研究旨在构建和验证印度年轻人的大脑 MRI 图谱及其相应的结构概率图谱。
这是一个特定于人群的图谱生成和验证过程。
招募了 100 名年龄在 21-30 岁的年轻健康成年人（M/F=50/50）参与研究。使用三种不同的 1.5-T 扫描仪进行图像采集。使用非刚性分组配准和标签传输技术创建图谱和结构图谱。
生成的图谱与其他图谱进行了比较，以研究特定于人群的趋势。
基于图谱的比较表明，印度人和高加索人大脑的整体大小存在显著差异。这一差异在三个全局指标（即长度、宽度和高度）上均有显著意义。与中国和韩国的脑模板进行这种比较表明，这三个脑模板在长度上是可比的，但在高度和宽度上存在显著差异（较小）。
研究结果证实，印度、中国和高加索人群之间的大脑形态存在显著差异。
