Ng P L, Higgins D A
Immunology. 1986 Jun;58(2):323-7.
Immunoglobulin (Ig) of a single class was found in duck (Anas platyrhynchos) bile. Its molecular weight was 890,000; serum IgM was 800,000. Heavy chains were 75,000 for bile Ig, 86,000 for IgM, 67,000 for 7.8S IgG and 37,000 for 5.7S IgG. Antigenic comparison showed that bile Ig resembled IgM but carried additional determinants. The ontogeny of bile Ig was distinct from that of serum IgM and IgG. Thus, duck bile Ig appears to be an IgM-like molecule secreted independently of serum Ig.
在鸭(绿头鸭)胆汁中发现了单一类别的免疫球蛋白(Ig)。其分子量为890,000;血清IgM为800,000。胆汁Ig的重链为75,000,IgM的重链为86,000,7.8S IgG的重链为67,000,5.7S IgG的重链为37,000。抗原比较表明,胆汁Ig与IgM相似,但带有额外的决定簇。胆汁Ig的个体发生与血清IgM和IgG不同。因此,鸭胆汁Ig似乎是一种独立于血清Ig分泌的类IgM分子。