Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen Centre for Astroparticle Physics, 91058, Erlangen, Germany.
Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Pattern Recognition Lab, 91058, Erlangen, Germany.
Sci Rep. 2019 Mar 12;9(1):4199. doi: 10.1038/s41598-018-38030-3.
Compared to conventional attenuation x-ray radiographic imaging, the x-ray Talbot-Lau technique provides further information about the scattering and the refractive properties of the object in the beam path. Hence, this additional information should improve the diagnostic process concerning medical applications and non-destructive testing. Nevertheless, until now, due to grating fabrication process, Talbot-Lau imaging suffers from small grating sizes (70 mm diameter). This leads to long acquisition times for imaging large objects. Stitching the gratings is one solution. Another one consists of scanning Talbot-Lau setups. In this publication, we present a compact and very fast scanning setup which enables imaging of large samples. With this setup a maximal scanning velocity of 71.7 mm/s is possible. A resolution of 4.1 lines/mm can be achieved. No complex alignment procedures are necessary while the field of view comprises 17.5 × 150 cm. An improved reconstruction algorithm concerning the scanning approach, which increases robustness with respect to mechanical instabilities, has been developed and is presented. The resolution of the setup in dependence of the scanning velocity is evaluated. The setup imaging qualities are demonstrated using a human knee ex-vivo as an example for a high absorbing human sample.
与传统衰减射线照相成像相比，X 射线泰伯-劳（Talbot-Lau）技术提供了关于光束路径中物体散射和折射特性的进一步信息。因此，这些额外的信息应该会改善医疗应用和无损检测方面的诊断过程。然而，到目前为止，由于光栅制造工艺的原因，泰伯-劳成像受到小光栅尺寸（70mm 直径）的限制。这导致对大型物体进行成像的采集时间很长。光栅拼接是一种解决方案。另一种方法是扫描泰伯-劳系统。在本出版物中，我们提出了一种紧凑且非常快速的扫描装置，它可以对大型样本进行成像。使用该装置，可以实现最大 71.7mm/s 的扫描速度。可以达到 4.1 线/mm 的分辨率。在视场包括 17.5×150cm 的情况下，不需要复杂的对准程序。针对扫描方法，已经开发并提出了一种改进的重建算法，它提高了对机械不稳定性的鲁棒性。评估了该装置的分辨率与扫描速度的关系。使用人膝盖离体作为高吸收人体样本的示例，演示了该装置的成像质量。
