Yu Lan, Xing Zhi-Kai, Mi Shuang-Li, Wu Xia
Key Laboratory of Collateral Disease Theory Research,School of Traditional Chinese Medicine,Capital Medical University Beijing 100069,China.
Key Laboratory of Precision Genomic Medicine,Beijing Institute of Genomics,Chinese Academy of Sciences Beijing 100101,China.
Zhongguo Zhong Yao Za Zhi. 2019 Jan;44(1):34-39. doi: 10.19540/j.cnki.cjcmm.20181101.013.
As a large micro-ecosystem in the human body,the intestinal microbiota is closely associated with the occurrence of many diseases.The clinical investigations and animal experiments have showed that traditional Chinese medicine(TCM) could maintain the balance of the intestinal micro-ecological system.This review summarized the research methods and literatures on the regulation effects of TCM,including different effective ingredients,extracts and Chinese herbal formulae,on intestinal microflora in recent five years,in order to provide a reference for the further research and development of TCM.
作为人体中的一个大型微生态系统,肠道微生物群与多种疾病的发生密切相关。临床研究和动物实验表明,中药可以维持肠道微生态系统的平衡。本文综述了近五年中药(包括不同有效成分、提取物和中药方剂)对肠道微生物群调节作用的研究方法和文献,为中药的进一步研发提供参考。