Department of Dermatology, Centre Hospitalier Universitaire Nice, Université Côté d'Azur, Nice, France.
INSERM U1065, Team 12, C3M, Université Côté d'Azur, Nice, France.
J Eur Acad Dermatol Venereol. 2019 Jun;33(6):987-1005. doi: 10.1111/jdv.15497. Epub 2019 Mar 14.
Lasers and intense pulsed light sources (IPLS) are proposed for the treatment of many pigmentary disorders. They are sometimes considered as magic tools able to remove any type of lesions. Although being the best option for several hyperpigmented lesions, they can also worsen some conditions and have potential side-effects.
The aim of this review was to give evidence-based recommendations for the use of lasers and IPLS in the treatment of hyperpigmented lesions.
These recommendations were produced for the European Society of Laser Dermatology by a consensus panel made up of experts in the field of pigment laser surgery. Recommendations on the use of lasers and light treatments were made based on the quality of evidence for efficacy, safety, tolerability, cosmetic outcome, patient satisfaction/preference and, where appropriate, on the experts' opinion.
Lasers and IPLS are very effective for treating many hyperpigmented lesions such as lentigos, dermal hypermelanocytosis or heavy metal depositions. In the other hand, they have to be considered with great caution for other disorders, such as café au lait macules, melasma or postinflammatory hyperpigmentation. After making the correct diagnosis, if lasers or IPLS are indicated, the optimal wavelengths and parameters will be chosen taking into account the skin phototype, origin and depth of the target pigments.
Although potentially very effective, lasers and IPLS cannot be proposed for all types of hyperpigmented lesions. In all cases, precise recognition of the disorder is mandatory for choosing between these devices and other therapeutic approaches.
激光和强脉冲光(IPLS)被提议用于治疗许多色素障碍。它们有时被认为是能够去除任何类型病变的神奇工具。虽然它们是几种色素沉着病变的最佳选择,但它们也可能使某些情况恶化,并具有潜在的副作用。
本综述的目的是为激光和 IPLS 在治疗色素沉着病变中的应用提供循证建议。
这些建议是由色素激光手术领域的专家组成的共识小组为欧洲激光皮肤科学会制定的。基于疗效、安全性、耐受性、美容效果、患者满意度/偏好的证据质量,以及在适当情况下基于专家意见,对激光和光疗的使用提出了建议。
激光和 IPLS 非常有效地治疗许多色素沉着病变,如雀斑、真皮性黑素细胞增多症或重金属沉积。另一方面,对于其他疾病,如咖啡牛奶斑、黄褐斑或炎症后色素沉着,必须谨慎考虑。在做出正确的诊断后,如果需要激光或 IPLS,将根据皮肤光型、靶色素的来源和深度选择最佳波长和参数。
虽然潜在地非常有效,但激光和 IPLS 不能用于所有类型的色素沉着病变。在所有情况下,为了在这些设备和其他治疗方法之间进行选择,必须准确识别病变。