Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore, 539747, Singapore.
Department of Early Psychosis Intervention, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore, 539747, Singapore.
BMC Psychiatry. 2019 Mar 15;19(1):91. doi: 10.1186/s12888-019-2073-z.
Hazardous alcohol use has often been found to be more prevalent amongst psychiatric outpatients than the general population. Additionally, it has also been associated with poorer outcomes. The study aimed to investigate (1) the prevalence and (2) socio-demographic and clinical correlates of hazardous alcohol use, as well as (3) the relationship between hazardous alcohol use and quality of life in an outpatient sample with First Episode Psychosis (FEP) in Singapore.
Baseline data (N = 280) was extracted from a longitudinal study investigating smoking and alcohol use amongst outpatients with FEP in a psychiatric hospital. Information on socio-demographics, hazardous alcohol use, and quality of life was collected through a self-report survey. Hazardous alcohol use was ascertained by total scores of 8 or higher on the Alcohol Use Disorders Identification Test (AUDIT). Data was analysed using logistic regression and linear regression analyses.
The prevalence of hazardous alcohol use over the past 12-month period was 12.9%. Those who had never smoked in their lifetime (vs current smokers) and those with a diagnosis of brief psychotic disorder (vs schizophrenia spectrum disorders) were found to have significantly lower odds of hazardous alcohol use. Hazardous alcohol use was also associated with lower negative symptom scores. Lastly, hazardous alcohol use was found to significantly predict lower scores on the physical health, social relationship and environment domains of quality of life.
The association between hazardous alcohol use and lower negative symptom scores is a surprising finding that needs to be further explored. The significant impact of hazardous alcohol use in reductions in quality of life suggests that early screening and interventions could benefit patients with hazardous alcohol use and comorbid psychosis.
在精神科门诊患者中，危险饮酒的发生率通常高于普通人群。此外，它还与较差的预后有关。本研究旨在调查（1）在新加坡的精神病门诊首发患者（FEP）中，危险饮酒的发生率，（2）社会人口统计学和临床相关因素，以及（3）危险饮酒与生活质量之间的关系。
从一项调查精神病门诊首发患者吸烟和饮酒情况的纵向研究中提取了基线数据（N=280）。通过自我报告调查收集了社会人口统计学、危险饮酒和生活质量信息。通过酒精使用障碍识别测试（AUDIT）的总分 8 分或以上来确定危险饮酒。使用逻辑回归和线性回归分析进行数据分析。
在过去 12 个月期间，危险饮酒的患病率为 12.9%。那些一生中从未吸烟过（与当前吸烟者相比）和那些被诊断为短暂精神病性障碍（与精神分裂症谱系障碍相比）的患者，其危险饮酒的可能性显著降低。危险饮酒也与较低的阴性症状评分相关。最后，危险饮酒与生活质量的身体健康、社会关系和环境领域的得分较低显著相关。
危险饮酒与较低的阴性症状评分之间的关联是一个令人惊讶的发现，需要进一步探讨。危险饮酒对生活质量的显著影响表明，早期筛查和干预可能使危险饮酒和合并精神病的患者受益。
