Department of Emergency Medicine, Faculty of Medicine, Ataturk University, 25240 Erzurum, Turkey.
Am J Emerg Med. 2019 Nov;37(11):2061-2065. doi: 10.1016/j.ajem.2019.02.042. Epub 2019 Feb 28.
Acute musculoskeletal injuries are one of the most common painful presentation when admission to the emergency department. The aim of the study is to compare the tenoxicam mesotherapy with intravenous dexketoprofen in pain control in patients with acute musculoskeletal injury.
This parallel randomized controlled trial was conducted with the patients admitted to the emergency department with musculoskeletal injury. Intravenous dexketoprofen was administered to the control group, and mesotherapy treatment was performed to the other group. Differences between 10th, 30th, 60th and 120th minutes VAS scores and on the admission VAS score, clinically meaningful change in pain intensity, and adverse effect of the procedures were compared among groups.
The differences in VAS scores and the presence of clinically meaningful change in pain intensity were statistically significantly higher in mesotherapy group than the systemic therapy group in all time periods. During one-week follow-up period, there was no reported adverse effect neither in mesotherapy group nor in the systemic therapy group.
The mesotherapy treatment may be superior than the systemic therapy for pain relief in musculoskeletal injury in short term follow-up in emergency department settings.
急性肌肉骨骼损伤是急诊科就诊时最常见的疼痛表现之一。本研究旨在比较急性肌肉骨骼损伤患者中应用替莫唑胺间充质疗法与静脉注射右酮洛芬在疼痛控制方面的效果。
这是一项在急诊科就诊的肌肉骨骼损伤患者中进行的平行随机对照试验。对照组给予静脉注射右酮洛芬，治疗组给予间充质治疗。比较两组患者在第 10、30、60 和 120 分钟时的 VAS 评分差异以及入院时 VAS 评分差异、疼痛强度的临床显著变化以及程序的不良反应。
在所有时间段，间充质治疗组的 VAS 评分差异和疼痛强度的临床显著变化发生率均显著高于全身治疗组。在为期一周的随访期间，间充质治疗组和全身治疗组均未报告不良反应。
在急诊科环境下，与全身治疗相比，间充质治疗可能在短期随访中更能缓解肌肉骨骼损伤引起的疼痛。
