Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia; Alma Mater Europaea - European Center Maribor (AMEU-ECM), Maribor, Slovenia.
Bosn J Basic Med Sci. 2019 Aug 20;19(3):297-303. doi: 10.17305/bjbms.2019.3949.
The meninges are involved in various pathologies and are often directly or indirectly severed during surgical procedures, especially the dura mater. This can pose a real challenge for the surgeon, as a proper reconstruction of the meninges is important to prevent complications such as cerebrospinal fluid leak (CSF). A variety of techniques for dural reconstruction have been described, employing natural and artificial materials. A novel technique for dural reconstruction involves soft tissue grafts in the form of fibrous or fibromuscular flaps, which are placed on the dural defects to seal the gaps. These soft tissue grafts represent an appropriate scaffold for cell ingrowth and fibrosis, thus preventing CSF. In this pilot study, we described the application of soft tissue grafts for dural reconstruction in 10 patients who underwent convexity meningioma surgery.
脑膜参与各种病理过程，并且在手术过程中经常会直接或间接地被切断，尤其是硬脑膜。这对外科医生来说是一个真正的挑战，因为脑膜的适当重建对于预防诸如脑脊液漏（CSF）等并发症非常重要。已经描述了各种硬脑膜重建技术，包括使用天然和人工材料。一种新的硬脑膜重建技术涉及纤维或纤维肌肉瓣形式的软组织移植物，将其放置在硬脑膜缺损处以密封间隙。这些软组织移植物是细胞内陷和纤维化的合适支架，从而防止 CSF。在这项初步研究中，我们描述了在 10 例接受凸面脑膜瘤手术的患者中应用软组织移植物进行硬脑膜重建的情况。
