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电子烟中香味化合物的蒸发行为研究。

Investigation of the evaporation behavior of aroma compounds in e-cigarettes.

机构信息

Institute of Analytical Chemistry and Radiochemistry, University of Innsbruck, CCB- Center of Chemistry and Biomedicine, Innrain 80-82, 6020, Innsbruck, Austria.

Austrian Drug Screening Institute, Innrain 66a, 6020, Innsbruck, Austria.

出版信息

Anal Bioanal Chem. 2019 May;411(14):3029-3035. doi: 10.1007/s00216-019-01749-7. Epub 2019 Mar 16.

DOI:10.1007/s00216-019-01749-7
PMID:30879113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6526143/
Abstract

The aim of this work was to evaluate the evaporation behavior of certain aroma compounds found in e-liquids. Since an e-liquid is evaporated, the aroma present can reach the lungs and could be absorbed into the body which may have long-term health effects above critical concentrations. Due to a lack in regulations, the sort and concentration of the compounds in sold e-liquids can vary. To capture the aroma compounds in the vapor, a smoking machine was developed. The resulting data represent the amount of aroma reaching the consumers' lungs. The influence of the e-cigarette temperature, ranging from 100 to 315 °C, on the evaporation of benzaldehyde, estragole, and different terpenoids was examined. Additionally, the effect of the liquid base composition on the amount of aroma in the vapor was compared using the analysis of variances. The influence of high temperature, the type of e-cigarette, and the atomizer coil material, which could lead to oxidation of limonene and linalool in the vapor, is shown here.

摘要

这项工作的目的是评估电子烟液中某些香气化合物的蒸发行为。由于电子烟液会蒸发,其中的香气可能会到达肺部并被人体吸收,超过临界浓度可能会对健康产生长期影响。由于缺乏监管,销售的电子烟液中化合物的种类和浓度可能会有所不同。为了捕捉蒸汽中的香气化合物,开发了一种吸烟机。所得数据代表到达消费者肺部的香气量。研究了电子烟温度(100 至 315°C)对苯甲醛、茴香脑和不同萜烯蒸发的影响。此外,还使用方差分析比较了液体基组成对蒸汽中香气含量的影响。这里显示了高温、电子烟类型和雾化器线圈材料的影响,这可能导致蒸汽中柠檬烯和芳樟醇氧化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/64c784b170a3/216_2019_1749_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/57cbe03dc163/216_2019_1749_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/948146466b7c/216_2019_1749_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/052f3d3f058b/216_2019_1749_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/9768a464a370/216_2019_1749_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/64c784b170a3/216_2019_1749_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/57cbe03dc163/216_2019_1749_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/948146466b7c/216_2019_1749_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/052f3d3f058b/216_2019_1749_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/9768a464a370/216_2019_1749_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9597/6526143/64c784b170a3/216_2019_1749_Fig5_HTML.jpg

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本文引用的文献

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J Anal Toxicol. 2018 Oct 1;42(8):537-543. doi: 10.1093/jat/bky056.
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Respiratory irritants in e-cigarette refill liquids across nine European countries: a threat to respiratory health?九个欧洲国家电子烟补充液中的呼吸道刺激物:对呼吸道健康的威胁?
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