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营养状况作为炎症性肠病住院治疗的预测指标:综述

Nutritional status as a predictor of hospitalization in inflammatory bowel disease: A review.

作者信息

Rocha Raquel, Sousa Uli H, Reis Thamiris L M, Santana Genoile O

机构信息

Escola de Nutrição, Universidade Federal da Bahia, Salvador 40110-150, Bahia, Brazil.

Pós graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador 40110-060, Bahia, Brazil.

出版信息

World J Gastrointest Pharmacol Ther. 2019 Mar 7;10(2):50-56. doi: 10.4292/wjgpt.v10.i2.50.

Abstract

BACKGROUND

Inflammatory bowel disease (IBD) presents an inflammatory picture that in the long run can lead to complications and consequently more hospitalizations compared to other diseases.

AIM

To evaluate the influence of nutritional status on the occurrence of IBD-related hospitalization.

METHODS

This integrative review was conducted in the online databases PubMed and MEDLINE, using the terms "obesity" and "malnutrition" accompanied by "hospitalization", each combined with "Crohn's disease" or "ulcerative colitis". Only studies conducted with humans, adults, and published in English or Spanish were selected, and those that were not directly associated with nutritional status and hospitalization were excluded from this review. The Preferred Reporting Items for Systematic Reviews and Meta-Analyzes guide was used as the basis for selection of studies.

RESULTS

Of the 80 studies identified, only five met the proposal of this review. None evaluated the association of good nutritional status with the risk of hospitalization. Malnutrition had a strong correlation with the risk of hospitalization related to IBD, and there was disagreement among three studies regarding the association of obesity and hospitalization rates.

CONCLUSION

Few studies have evaluated nutritional status as a predictor of IBD-related hospitalization. The presence of malnutrition appears to be associated with hospitalization in these patients, but further studies are needed to elucidate the issue.

摘要

背景

炎症性肠病(IBD)呈现出一种炎症状态,从长远来看,与其他疾病相比,它可能导致并发症,进而增加住院次数。

目的

评估营养状况对IBD相关住院发生率的影响。

方法

在在线数据库PubMed和MEDLINE中进行了这项综合综述,使用了“肥胖”和“营养不良”以及“住院”等术语,每个术语都与“克罗恩病”或“溃疡性结肠炎”相结合。仅选择了针对人类、成年人且以英文或西班牙文发表的研究,那些与营养状况和住院没有直接关联的研究被排除在本综述之外。系统评价和荟萃分析的首选报告项目指南被用作研究选择的基础。

结果

在确定的80项研究中,只有5项符合本综述的提议。没有一项研究评估良好营养状况与住院风险的关联。营养不良与IBD相关住院风险有很强的相关性,并且在三项研究中关于肥胖与住院率的关联存在分歧。

结论

很少有研究将营养状况评估为IBD相关住院的预测因素。营养不良的存在似乎与这些患者的住院有关,但需要进一步研究来阐明这个问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7b3/6422851/e9c59c434a90/WJGPT-10-50-g001.jpg

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