School of Biomedical Sciences, Faculty of Medicine and Dentistry, University of Plymouth , Plymouth , UK.
Int J Food Sci Nutr. 2019 Nov;70(7):894-900. doi: 10.1080/09637486.2019.1585418. Epub 2019 Mar 20.
Substituting sugar-sweetened for artificially sweetened beverages may reduce energy intakes. This study aims to ascertain the acute glycaemic effects of the NNS aspartame and acesulfame-K in UK diet-cola (DC). Ten healthy participants attended the laboratory fasted on three occasions. Individuals drank (1) 25 g glucose in 125 mL water + 236 mL water, (2) 25 g glucose in 125 mL water with 236 mL DC and (3) 236 mL sucrose-sweetened cola with 125 mL water. Blood (glucose) was measured pre-test and every 15 minutes over a 120-minute period using portable glucometers. The glucose-control and glucose + DC elicited similar blood glucose rises above pre-prandial levels. Sucrose-sweetened cola showed a non-significant lower rise in postprandial glycaemia, exhibiting the lowest glycaemic index (GI) (77.0 ± 9.1). GI of glucose (100.0 ± 15.2) and glucose + DC (104.3 ± 8.5) was similar and a one-way repeated-measures ANOVA showed no significant differences in glycaemic response between test drinks ((2,29) = 1.68, > .05). Results demonstrate the glycaemic inactivity of non-nutritive sweeteners.
用人工甜味剂替代含糖饮料可能会降低能量摄入。本研究旨在确定英国低糖可乐（DC）中代糖天门冬酰苯丙氨酸甲酯和乙酰磺胺酸钾的急性血糖效应。10 名健康参与者在空腹状态下分别参加了 3 次实验室试验。个体分别饮用了（1）25g 葡萄糖+125ml 水+236ml 水，（2）25g 葡萄糖+125ml 水+236ml DC，（3）125ml 水+236ml 蔗糖可乐。使用便携式血糖仪在测试前和 120 分钟内的每 15 分钟测量一次血液（血糖）。葡萄糖对照和葡萄糖+DC 引起的餐后血糖升高与餐前水平相似。蔗糖可乐的餐后血糖升高幅度较低，但差异无统计学意义，血糖指数（GI）最低（77.0±9.1）。葡萄糖（100.0±15.2）和葡萄糖+DC（104.3±8.5）的 GI 相似，单向重复测量方差分析显示，测试饮料之间的血糖反应无显著差异（(2,29)=1.68，>.05）。结果表明，非营养性甜味剂没有血糖活性。
