Peypoux F, Pommier M T, Marion D, Ptak M, Das B C, Michel G
J Antibiot (Tokyo). 1986 May;39(5):636-41. doi: 10.7164/antibiotics.39.636.
The structure of mycosubtilin, a peptidolipid antibiotic from Bacillus subtilis, was revised by FAB mass spectrometry, 2D NMR spectrometry and also by Edman degradation of the peptide resulting from the N-bromosuccinimide reaction. Four homologous beta-amino acid components were identified by capillary gas chromatography. The cyclopeptide mycosubtilin consists of seven alpha-amino acids in an LDDLLDL sequence closed by a beta-amino acid linkage similar to that found in other antibiotics of the iturin group.
