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槲皮素及其配合物的药用抗氧化活性。

Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application.

机构信息

Research Center of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.

出版信息

Molecules. 2019 Mar 21;24(6):1123. doi: 10.3390/molecules24061123.

DOI:10.3390/molecules24061123
PMID:30901869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6470739/
Abstract

Quercetin is a bioactive compound that is widely used in botanical medicine and traditional Chinese medicine due to its potent antioxidant activity. In recent years, antioxidant activities of quercetin have been studied extensively, including its effects on glutathione (GSH), enzymatic activity, signal transduction pathways, and reactive oxygen species (ROS) caused by environmental and toxicological factors. Chemical studies on quercetin have mainly focused on the antioxidant activity of its metal ion complexes and complex ions. In this review, we highlight the recent advances in the antioxidant activities, chemical research, and medicinal application of quercetin.

摘要

槲皮素是一种生物活性化合物,由于其强大的抗氧化活性,在植物药和中药中被广泛应用。近年来,人们对槲皮素的抗氧化活性进行了广泛的研究,包括其对谷胱甘肽(GSH)、酶活性、信号转导途径以及环境和毒理学因素引起的活性氧(ROS)的影响。槲皮素的化学研究主要集中在其金属离子配合物和络合离子的抗氧化活性上。在这篇综述中,我们重点介绍了槲皮素抗氧化活性、化学研究和药用应用的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/94c680c89669/molecules-24-01123-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/fb5150daa31d/molecules-24-01123-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/0c1afdc76db1/molecules-24-01123-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/94c680c89669/molecules-24-01123-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/fb5150daa31d/molecules-24-01123-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/0c1afdc76db1/molecules-24-01123-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc84/6470739/94c680c89669/molecules-24-01123-g003.jpg

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Quercetin nanoparticles with enhanced bioavailability as multifunctional agents toward amyloid induced neurotoxicity.具有增强生物利用度的槲皮素纳米颗粒作为针对淀粉样蛋白诱导的神经毒性的多功能剂。
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Oxidative stress: the lowest common denominator of multiple diseases.
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Investigation of the inhibitory effects of total flavonoids of litchi seed on -induced liver damage and fibrosis.荔枝核总黄酮对诱导性肝损伤和肝纤维化的抑制作用研究。
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Potential of Quercetin as a Promising Therapeutic Agent Against Type 2 Diabetes.槲皮素作为一种有前景的抗2型糖尿病治疗药物的潜力。
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