同种异体移植物在后交叉韧带重建中的应用：健康经济学视角。
Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective.
机构信息
Division of Health Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Campus, Coventry, CV4 7AL, UK.
Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.
出版信息
Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1810-1816. doi: 10.1007/s00167-019-05477-4. Epub 2019 Mar 22.
Abstract
PURPOSE
To review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament.
METHODS
Systematic review and cost-effectiveness analysis.
RESULTS
The available evidence does not show any significant difference in clinical effectiveness between autografts and allografts. Given that, only a cost analysis is provided, which shows that allografts are more costly.
CONCLUSION
Given the lack of any benefit of allografts over autografts, autografts should be preferred on cost grounds, if available. However, there may be situations where an allograft is indicated, for example, in multiple ligament reconstructions.
LEVEL OF EVIDENCE
IV.
摘要
目的
回顾同种异体移植物和自体移植物在后交叉韧带重建中的相对成本效益。
方法
系统评价和成本效益分析。
结果
现有证据表明，同种异体移植物和自体移植物在临床疗效上没有显著差异。鉴于此，仅提供了成本分析，结果表明同种异体移植物的成本更高。
结论
鉴于同种异体移植物并不优于自体移植物，在有条件的情况下，出于成本考虑，应优先选择自体移植物。但是，在某些情况下可能需要使用同种异体移植物，例如在多韧带重建中。
证据等级
IV 级。
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