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孕中期人类胎儿的血气及酸碱状态

Blood gases and acid-base status of the human second-trimester fetus.

作者信息

Soothill P W, Nicolaides K H, Rodeck C H, Gamsu H

出版信息

Obstet Gynecol. 1986 Aug;68(2):173-6.

PMID:3090491
Abstract

Maternal arterial, umbilical venous, and umbilical arterial blood were obtained at fetoscopy in the second trimester and analyzed for blood gases and acid-base indexes. In comparing umbilical venous (N = 31) with maternal arterial (N = 39) samples, the mean (+/- SD) PO2 was lower (55 +/- 7 versus 100 +/- 15 mmHg, P less than .001) and PCO2 (37 +/- 4 versus 34 +/- 4 mmHg), bicarbonate (20 +/- 2.0 versus 18.5 +/- 1.5 mmol/L), lactate (1.10 +/- 0.25 versus 0.80 +/- 0.30 mmol/L), and base excess (-4.2 +/- 2.3 versus -6.0 +/- 1.5 mmol/L) were higher (P less than .001). The mean umbilical venous pH did not differ significantly from the maternal arterial (7.358 +/- 0.040 versus 7.373 +/- 0.035). Comparing umbilical arterial (N = 21) with umbilical venous (N = 31) samples, the PO2 level was lower (34 +/- 4 versus 55 +/- 7 mmHg, P less than .001) and PCO2 higher (42 +/- 4 verus 37 +/- 4 mmHg, (P less than .001); the pH was marginally lower (7.339 +/- 0.03 versus 7.358 +/- 0.040; P less than .05) and bicarbonate higher (22 +/- 1.5 versus 20 +/- 2.0 mmol/L, P less than .001). Umbilical arterial and umbilical venous values were similar in the case of lactate and base excess.

摘要

在孕中期进行胎儿镜检查时采集母体动脉血、脐静脉血和脐动脉血,并分析血气和酸碱指标。将脐静脉血样本(N = 31)与母体动脉血样本(N = 39)进行比较,脐静脉血的平均(±标准差)氧分压较低(55±7对100±15 mmHg,P<0.001),而二氧化碳分压(37±4对34±4 mmHg)、碳酸氢盐(20±2.0对18.5±1.5 mmol/L)、乳酸(1.10±0.25对0.80±0.30 mmol/L)和碱剩余(-4.2±2.3对-6.0±1.5 mmol/L)较高(P<0.001)。脐静脉血的平均pH值与母体动脉血无显著差异(7.358±0.040对7.373±0.035)。将脐动脉血样本(N = 21)与脐静脉血样本(N = 31)进行比较,脐动脉血氧分压水平较低(34±4对55±7 mmHg,P<0.001),二氧化碳分压较高(42±4对37±4 mmHg,P<0.001);pH值略低(7.339±0.03对7.358±0.040;P<0.05),碳酸氢盐较高(22±1.5对20±2.0 mmol/L,P<0.001)。脐动脉血和脐静脉血的乳酸和碱剩余值相似。

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