Yamashita Tomohisa, Yasukawa Kazuyuki, Yunoki Etsuko
Toyama Institute of Health.
Anal Sci. 2019 Jul 10;35(7):769-775. doi: 10.2116/analsci.18P554. Epub 2019 Mar 22.
Fluidic chip fabrication technologies using three-dimensional (3D) printing have received broad attention recently. Herein, we describe a new method for fabricating polydimethylsiloxane (PDMS) fluidic chips using a 3D-printed polyvinyl alcohol (PVA) or acrylonitrile butadiene styrene (ABS) template and polymer coating. In this method, polyethylene glycol (PEG) was coated on the 3D-printed template. This coated template was immersed in liquid PDMS, and subsequently the PDMS was cured. Space can be created between the template and PDMS by removing this liquid PEG from the channel. This space renders template removal easier. A flow path is formed by dissolving the template with a solvent. These PDMS chips are used for flow injection measurement.
近年来，利用三维（3D）打印的流体芯片制造技术受到了广泛关注。在此，我们描述了一种使用3D打印的聚乙烯醇（PVA）或丙烯腈-丁二烯-苯乙烯（ABS）模板以及聚合物涂层来制造聚二甲基硅氧烷（PDMS）流体芯片的新方法。在该方法中，将聚乙二醇（PEG）涂覆在3D打印的模板上。将此涂覆的模板浸入液态PDMS中，随后使PDMS固化。通过从通道中去除这种液态PEG，可以在模板和PDMS之间形成空间。该空间使模板去除更容易。通过用溶剂溶解模板形成流动路径。这些PDMS芯片用于流动注射测量。
