Severino Paolo, Mariani Marco Valerio, Maraone Annalisa, Piro Agostino, Ceccacci Andrea, Tarsitani Lorenzo, Maestrini Viviana, Mancone Massimo, Lavalle Carlo, Pasquini Massimo, Fedele Francesco
Department of Cardiovascular, Respiratory, Anesthesiology, Nephrology and Geriatric Sciences, Sapienza University of Rome, Rome, Italy.
Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Cardiol Res Pract. 2019 Feb 18;2019:1208505. doi: 10.1155/2019/1208505. eCollection 2019.
Atrial fibrillation (AF) is the most widely recognized arrhythmia. Systemic arterial hypertension, diabetes, obesity, heart failure, and valvular heart diseases are major risk factors for the onset and progression of AF. Various studies have emphasized the augmented anxiety rate among AF patients due to the poor quality of life; however, little information is known about the possibility of triggering atrial fibrillation by anxiety. The present review sought to underline the possible pathophysiological association between AF and anxiety disorders and suggests that anxiety can be an independent risk factor for AF, acting as a trigger, creating an arrhythmogenic substrate, and modulating the autonomic nervous system. The awareness of the role of anxiety disorders as a risk factor for AF may lead to the development of new clinical strategies for the management of AF.
心房颤动(AF)是最广为人知的心律失常。系统性动脉高血压、糖尿病、肥胖、心力衰竭和心脏瓣膜病是房颤发生和进展的主要危险因素。各种研究都强调了房颤患者由于生活质量差而导致的焦虑率增加;然而,关于焦虑引发房颤的可能性却知之甚少。本综述旨在强调房颤与焦虑症之间可能存在的病理生理联系,并表明焦虑可能是房颤的独立危险因素,可作为触发因素、形成致心律失常基质并调节自主神经系统。认识到焦虑症作为房颤危险因素的作用可能会促使开发新的房颤管理临床策略。