Department of Medicine, New York University School of Medicine, New York, New York.
Department of Rehabilitation Medicine, New York University Langone Medical Center, New York, New York.
J Palliat Med. 2019 Oct;22(10):1196-1201. doi: 10.1089/jpm.2018.0529. Epub 2019 Mar 25.
Research on the patterns of use of medical cannabis among cancer patients is lacking. To describe patterns of medical cannabis use by patients with cancer, and how patterns differ from patients without cancer. We performed secondary data analysis using data from a medical cannabis licensee in New York State, analyzing demographic information, qualifying conditions, and symptoms, and the medical cannabis product used, including tetrahydrocannabinol (THC) to cannabidiol (CBD) ratios. Adults age ≥18 who used New York State medical cannabis licensee products between January 2016 and December 2017. There were a total of 11,590 individuals with 1990 (17.2%) having cancer who used at least one cannabis product. Patients with cancer using cannabis were older and more likely to be female. The most common qualifying symptom for both cancer and noncancer patients was severe or chronic pain. Cancer patients were more likely to use the sublingual tincture form of cannabis ( = 1098, 55.2%), while noncancer patients were more likely to use the vaporization form ( = 4222, 44.0%). Over time, across all patients, there was an increase in the THC daily dose by a factor of 0.20 mg/week, yielding a corresponding increase in the THC:CBD daily ratio. Compared with noncancer patients, these trends were not different in the cancer group for THC daily dose, but there were less pronounced increases in the THC:CBD daily ratio over time among cancer patients. Our study found some key differences in demographics and medical cannabis product use between patients with cancer and without cancer.
针对癌症患者医用大麻使用模式的研究较为匮乏。本研究旨在描述癌症患者医用大麻的使用模式,以及这些模式与非癌症患者之间的差异。我们对纽约州医用大麻许可持有者的数据进行了二次数据分析,分析了患者的人口统计学信息、合格条件、症状以及所使用的医用大麻产品,包括四氢大麻酚(THC)与大麻二酚(CBD)的比例。研究对象为 2016 年 1 月至 2017 年 12 月期间使用过纽约州医用大麻许可持有者产品的年龄≥18 岁的成年人。共有 11590 人患有癌症,其中 1990 人(17.2%)至少使用过一种大麻产品。使用大麻的癌症患者年龄更大,更可能为女性。严重或慢性疼痛是癌症和非癌症患者最常见的合格症状。癌症患者更可能使用舌下酊剂形式的大麻( = 1098,55.2%),而非癌症患者更可能使用汽化形式( = 4222,44.0%)。随着时间的推移,所有患者的 THC 日剂量增加了 0.20mg/周,相应的 THC:CBD 日剂量比也增加了。与非癌症患者相比,癌症患者的 THC 日剂量呈上升趋势,但 THC:CBD 日剂量比的上升幅度较小。本研究发现,癌症患者和非癌症患者在人口统计学和医用大麻产品使用方面存在一些关键差异。