From the Department of Neurology (D.B.), Oregon Health & Science University, Portland; and Department of Neurology (C.S.D.), University of California-Davis.
Neurology. 2019 Mar 26;92(13):631-634. doi: 10.1212/WNL.0000000000007176.
With the long-term goal of improving community health by screening for dementia, we tested the utility of integrating the Six-Item Screener (SIS) into our emergency department neurology consultations.
In this cross-sectional observational study, we measured SIS performance within 24 hours of hospital arrival in 100 consecutive English-speaking patients aged ≥45 years. Performance was compared to patient age, previously charted cognitive impairment, and proxies for in-hospital complexity: whether or not a patient was admitted to the hospital and the number of medical studies ordered.
Those with poor SIS performance were older ( = 0.02) and more likely to have previously charted cognitive impairment ( < 0.01; sensitivity 86%, specificity 77%). Poor performers were more likely to be admitted to the hospital ( = 0.04; odds ratio 3.6) and were subjected to more tests once admitted ( < 0.01), relationships that persisted after accounting for age and history of cognitive impairment.
Poor performance on the SIS was associated with previously charted cognitive impairment, justifying future study of its ability to detect unrecognized dementia cases. Until then, its ability to inexpensively anticipate medically complex hospital admissions motivates broader emergency department use of the SIS.
通过对痴呆症进行筛查,以期长期改善社区健康,我们检验了在我们的急诊神经科会诊中整合六项目简易筛查表(SIS)的效用。
在这项横断面观察性研究中,我们在入诊后 24 小时内对 100 名连续的、母语为英语的、年龄≥45 岁的患者进行了 SIS 表现测量。表现通过患者年龄、先前记录的认知障碍以及住院复杂性的替代指标(是否住院以及所下的医学检查数量)进行了对比。
SIS 表现不佳的患者年龄更大( = 0.02),更有可能存在先前记录的认知障碍( < 0.01;敏感性 86%,特异性 77%)。表现不佳者更有可能被收治入院( = 0.04;比值比 3.6),且一旦入院后接受的检查更多( < 0.01),这些关系在考虑到年龄和认知障碍病史后仍然存在。
SIS 表现不佳与先前记录的认知障碍相关,这证明了未来对其识别未被识别的痴呆病例的能力进行研究是合理的。在此之前,它能够经济有效地预测需要住院的复杂病例,这促使在更广泛的急诊部门使用 SIS。