Niu Jin-Mu, Zhang Jie, Qiu Xiao-Jian, Wang Juan, Pei Ying-Hua, Wang Yu-Ling, Wang Ting
Department of Respiration, Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, P.R. China.
Oncol Lett. 2019 Apr;17(4):3990-3996. doi: 10.3892/ol.2019.10051. Epub 2019 Feb 19.
Malignant carinal stenosis is a disease process that is not always suitable for treatment with a Y-shaped stent. When one of the main bronchi is completely obstructed and cannot be recanalized, or its distal lung tissue has lost function, inserting a Y-shaped stent is infeasible. In this complex condition, a cone-shaped stent is selected to maintain the patency of the trachea and the other main bronchus. The efficacy of the bare cone-shaped Micro-Tech stent to treat malignant carinal stenosis was evaluated in the current study. The medical records of 47 patients with malignant carinal stenosis who underwent Micro-Tech stent placement between January 2004 and October 2017 in Beijing Tian Tan Hospital (Beijing, China) were analyzed retrospectively. A total of 47 bare Micro-Tech stents (28 Y-shaped and 19 cone-shaped) were successfully inserted in the patients. Following stent placement, immediate satisfactory results were achieved in all patients, especially an improvement of dyspnea (100%), cough (81.1%) and stridor (100%). The Karnofsky scores were significantly increased (P<0.001), and the American Thoracic Society Dyspnea Index values were significantly decreased (P<0.001). Following a median of 88 days, initial bronchoscopic interventions were performed for tumor overgrowth (84.6%), stent fracture (7.7%) and granulation tissue (7.7%). Restenting was performed in two patients due to tumor progression (n=1) and stent fracture (n=1). Removal of a Y-shaped stent was attempted in one patient, but failed, as the stent had become partly embedded in the airway mucosa. In conclusion, cone-shaped Micro-Tech stent placement maintained tracheal-unilateral main bronchus patency and benefitted patients with malignant carinal stenosis in whom Y-shaped stents were not suitable for insertion.
恶性气管隆突狭窄是一种并非总是适合使用Y形支架治疗的疾病过程。当其中一个主支气管完全阻塞且无法再通,或者其远端肺组织已失去功能时,插入Y形支架是不可行的。在这种复杂情况下,选择锥形支架来维持气管和另一个主支气管的通畅。本研究评估了裸锥形迈柯唯(Micro-Tech)支架治疗恶性气管隆突狭窄的疗效。回顾性分析了2004年1月至2017年10月在北京天坛医院(中国北京)接受迈柯唯支架置入术的47例恶性气管隆突狭窄患者的病历。共成功为患者插入了47个裸迈柯唯支架(28个Y形和19个锥形)。支架置入后,所有患者均立即取得了满意的效果,尤其是呼吸困难(100%)、咳嗽(81.1%)和喘鸣(100%)得到改善。卡氏评分显著提高(P<0.001),美国胸科学会呼吸困难指数值显著降低(P<0.001)。中位88天后,因肿瘤过度生长(84.6%)、支架断裂(7.7%)和肉芽组织(7.7%)进行了首次支气管镜干预。由于肿瘤进展(n=1)和支架断裂(n=1),对2例患者进行了再次支架置入。试图在1例患者中取出Y形支架,但未成功,因为支架已部分嵌入气道黏膜。总之,锥形迈柯唯支架置入术维持了气管-单侧主支气管通畅,对不适合插入Y形支架的恶性气管隆突狭窄患者有益。