van Donselaar C A, Meerwaldt J D, van Gijn J
J Neurol Neurosurg Psychiatry. 1986 Sep;49(9):1071-3. doi: 10.1136/jnnp.49.9.1071.
In six patients an apnoea test was carried out to confirm brain death according to a protocol recommended in the USA. After ten minutes' apnoea the pCO2 did not reach the target value of 7.98 kPa (60 mm Hg) in any of these patients. This was caused by the low initial value and the slow increase of the pCO2. Moreover, we could not confirm the belief that the necessary duration of the apnoea test can be predicted by assuming a rise of the pCO2 of 0.33 kPa (2.5 mm Hg) per minute.
按照美国推荐的方案,对6例患者进行了呼吸暂停试验以确认脑死亡。呼吸暂停10分钟后,这些患者中没有一例的动脉血二氧化碳分压(pCO2)达到目标值7.98千帕(60毫米汞柱)。这是由于初始值较低以及pCO2上升缓慢所致。此外,我们无法证实这样一种观点,即通过假设pCO2每分钟上升0.33千帕(2.5毫米汞柱)就可以预测呼吸暂停试验的必要持续时间。